Abstract: It provides methods and pharmaceutical compositions comprising antagonists to the protein Bile Salt-Stimulated Lipase (BSSL) for the prevention, prophylaxis and treatment of inflammatory diseases, such as rheumatoid arthritis. It further relates to pharmaceutical compositions comprising BSSL antagonists and their use in methods for the prevention, prophylaxis and treatment of inflammatory diseases, such as rheumatoid arthritis. Suitable BSSL antagonists to be used according to the invention are BSSL antibodies.
Type:
Grant
Filed:
October 30, 2013
Date of Patent:
October 27, 2015
Assignee:
LIPUM AB
Inventors:
Olle Hernell, Susanne Lindquist, Lennart Gustav Lundberg