Abstract: The present invention is directed to methods for providing a peptide receptor radiotherapy treatment recommendation for a subject having a neuroendocrine tumor by determining the expression level of each of at least 9 biomarkers comprising ARAF1, BRAF, KRAS, RAF-1, ATP6V1H, OAZ2, PANK2, PLD3, and ALG9. In some embodiments, the methods can further include determining the expression level of each of NAP1L1, NOL3, and TECPR2.
Type:
Grant
Filed:
November 29, 2018
Date of Patent:
September 5, 2023
Assignee:
Liquid Biopsy Research LLC
Inventors:
Irvin Mark Modlin, Mark Kidd, Ignat Drozdov
Abstract: The present invention is directed to methods for detecting a colon cancer, methods for determining whether a colon cancer is stable or progressive, methods for determining a risk for disease relapse, and methods for determining a response by a subject having a colon cancer to a therapy.
Type:
Grant
Filed:
January 22, 2019
Date of Patent:
August 16, 2022
Assignee:
Liquid Biopsy Research LLC
Inventors:
Irvin Mark Modlin, Mark Kidd, Ignat Drozdov
Abstract: The present invention is directed to methods for detecting a prostate cancer, methods for determining whether a prostate cancer is stable or progressive, low or high Gleason score, methods for differentiating benign prostate hyperplasia (BPH) from prostate cancer, methods for determining the completeness of surgery, and methods for evaluating the response to a prostate cancer therapy.
Type:
Grant
Filed:
February 21, 2019
Date of Patent:
August 9, 2022
Assignee:
Liquid Biopsy Research LLC
Inventors:
Irvin Mark Modlin, Mark Kidd, Ignat Drozdov
Abstract: The present disclosure provides a buffer comprising at least one chaotropic agent, at least one chelating agent and at least one non-ionic surfactant, wherein the buffer stabilizes a biological sample at about room temperature for at least about one day.
Type:
Application
Filed:
October 8, 2020
Publication date:
April 15, 2021
Applicants:
Liquid Biopsy Research LLC
Inventors:
Mark KIDD, Irvin Mark MODLIN, Ignat DROZDOV