Abstract: A method of stimulating an immune response in a subject including administering a micrometer-sized particle coupled with an antigen to the subject, wherein increasing the aspect ratio of the micrometer-sized particle increases the immune response. A method of stimulating an immune response in a subject including administering to the subject a plurality of particles, wherein each particle is coupled with an immuno stimulating agent and a protein. A vaccine particle composition including a plurality of particles configured to release a first protein at a first rate and a second protein at a second rate and configured to provide priming and boosting capability in a single dose.
Type:
Application
Filed:
March 4, 2009
Publication date:
June 23, 2011
Applicant:
LIQUIKIA TECHNOLOGIES, INC.
Inventors:
Bolyn Hubby, Andrew Murphy, Jeff Kindig, Jesse White, Samantha Roth, Ashley L. Galloway, Laura Copp