Patents Assigned to Lisapharma Spa
  • Patent number: 5321013
    Abstract: Pharmaceutical compositions in the form of stable sucralfate suspensions free of suspending agents, wherein the sucralfate is present in the form of a gel having self-suspending properties and is suspended in an aqueous carbohydrate solution in a quantity of between 1 and 40% of sucralfate by weight.Said gel has a surface area exceeding 200 m.sup.2 /g and is prepared by dissolving powdered sucralfate in an HCl solution and then precipitating it with an NaOH solution added to a pH of between 4 and 4.5.
    Type: Grant
    Filed: January 8, 1990
    Date of Patent: June 14, 1994
    Assignee: Lisapharma SpA
    Inventors: Giorgio G. Z. Zagnoli, Ubaldo Conte, Paolo Colombo, Carla Caramella
  • Patent number: 4755533
    Abstract: This invention relates to the vaginal topical use of lysine p-isobutylphepropionate in local and targeted anti-inflammatory treatment of pathologies of obstetric and gynelogical type.Said use is effective in the treatment of patients with inflammatory forms having either aspecific or specific etiology, and also in the treatment both of patients of medical pertinence and of patients of surgical pertinence. The lysine p-isobutylphenylpropionate is used in the form of an aqueous solution for vaginal washes or in other pharmaceutical forms for vaginal use such as globules, suppositories etc.
    Type: Grant
    Filed: April 30, 1987
    Date of Patent: July 5, 1988
    Assignee: Laboratorio Italiano Biochimico Farmaceutico LISAPHARMA SpA
    Inventor: Giorgio Zagnoli
  • Patent number: 4605741
    Abstract: The present invention relates to a novel pharmacologically active salt derivative, constituted by 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxy-phenyl)-1-butanone 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde-5-phosphate, to the process for the production thereof, and to the related pharmaceutical compositions.Said salt derivative is produced by reacting 3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde-5-phosphoric acid with 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-3-butanone in an organic solvent and subsequently crystallizing the reaction product.Said salt derivative carries out an important pharmacological activity as inhibitor of platelet aggregation with vasodilative action.
    Type: Grant
    Filed: November 13, 1985
    Date of Patent: August 12, 1986
    Assignee: Lisapharma Spa
    Inventors: Giorgio Zagnoli, Ubaldo Conte, Paolo Colombo