Abstract: A method of delivering an agent to a mammal includes providing a device with an agent for delivery of the agent to anal and/or perianal tissues of the mammal. The device is inserted into an anus of the mammal and then an expandable portion of the device is expanded to anchor the device within the anus.
Abstract: A device is provided for delivery of a therapeutic agent to the anal and perianal regions. The device includes a deployable internal anchor adapted to comfortably anchor the device in the anal canal, a shaft adapted to store and release the agent to the anal canal, and an external bumper adapted to store and release the agent to the perianal tissue and externally anchor the device.
Abstract: A device is provided for delivery of a therapeutic agent to the anal and perianal regions. The device includes a deployable internal anchor adapted to comfortably anchor the device in the anal canal, a shaft adapted to store and release the agent to the anal canal, and an external bumper adapted to store and release the agent to the perianal tissue and externally anchor the device.