Inventors:
Rochus Emmanuel Jacob, Samuel Ward Kortz, Jason Evans Goulden, Adam Scott Kilgore, Rafat E. Mehdi, Mi Zhou, Benjamin Zachary Niewood, Amber Luttmann Volmering, Minjung Kim
Abstract: A new cultivar of Colorado blue spruce tree named ‘Wards Blue Waves’ characterized by its foliage that is silvery blue in appearance in color year around, its foliage with a very glaucous surface, its branch apexes that curve upwards, its dense and compact plant habit, its conical shape, and its short plant height; reaches 6 m after 20 years when grown in Oregon.
Abstract: The present invention provides novel piperidinyl-containing nociceptin receptor ligand compounds and pharmaceutical compositions useful in the treatment of neurological diseases and conditions where such ligands mediate the negative effects of the condition. Such neurological diseases and conditions include acute and chronic pain, substance abuse/dependence, alcohol addiction, anxiety, depression, sleep disorders, gastrointestinal disorders, renal disorders, cardiovascular disorders and Parkinson's disease.