Abstract: The present invention generally relates to in vitro methods for mimicking in vivo pathological or physiologic conditions. The methods comprise applying shear forces to a cell type or cell type plated on a surface within a cell culture container. Methods for testing drugs or compounds in such systems are also described.

Abstract: Methods and systems are provided for increasing an amount of oxygen in a pre-chamber of a cylinder prior to combustion. In one example, a method may include purging residual gases from a pre-chamber to a cylinder via a pre-chamber air injection, and reducing a flow of the oxygen from the pre-chamber to the cylinder via a cylinder fuel injection directed toward an orifice fluidically connecting the pre-chamber with the cylinder. In this way, a composition of pre-chamber gases may be adjusted during a combustion cycle of a cylinder.

Abstract: A catheter pump is provided that includes a rotatable impeller and an elongate cannula. The elongate cannula has a mesh that has a plurality of circumferential members disposed about the impeller. The elongate cannula has a plurality of axial connector extending between a proximal side of a distal circumferential member and a distal side of a proximal circumferential member. The circumferential members are radially self-expandable. The cannula is configured to minimize fracture within at least in the distal zone of the mesh as the elongated cannula moves into a sheathing device.

Abstract: A method for implanting a replacement heart valve within a diseased valve includes accessing a patient's heart by piercing a myocardium, advancing a guidewire into the patient's heart, and installing an access device in a wall of the heart. The access device preferably has at least one valve mechanism. A valve delivery device is advanced over the guidewire and through the access device. The valve delivery device has a replacement heart valve disposed along a distal end portion thereof. The replacement heart valve preferably includes an outer support structure and a leaflet valve disposed within the outer support structure. The replacement heart valve is radially expanded within the diseased valve. During implantation, the outer support structure conforms to a diameter of the diseased valve and the leaflet valve expands to a fixed size having a diameter smaller than the diameter of the diseased valve.

Abstract: Stable liquid formulations of GLP-1 and GLP-1 analogues and method of using such formulations in the treatment of disorders or conditions are provided.

Abstract: The present disclosure provides devices, systems and methods for monitoring unauthorized access into a container or bottle, and alerting the authorized user, or someone designated by the authorized user, of any unauthorized access.

Abstract: A core catcher for a coring tool may include a sleeve including a slit extending along at least a portion of a height of the sleeve. A crosspiece may extend at least partially across the at least one slit and at least partially around a perimeter of the sleeve. A track may extend at least partially around the perimeter of the sleeve, the crosspiece being slidably engaged with the track. The crosspiece and the track may be configured to cooperatively delimit relative movement of portions of the sleeve on opposite sides of the slit as a width of the slit increases or decreases responsive to receipt of a core sample into the core catcher.

Abstract: A wireless device may receive at least one message comprising configuration parameters of a plurality of cells being in a cross-carrier scheduling group comprising a first cell and a second cell. The first cell identified by a first cell identifier may employ a first number of bits. The configuration parameters may indicate that the second cell is a cross-carrier scheduling cell for the first cell. The configuration parameters may comprise the first cell identifier and a first cell indicator field. The first cell indicator field may employ a second number of bits. The wireless device may receive downlink control information via a control channel of the second cell for a packet transmitted via the first cell. The downlink control information may comprise the first cell indicator field identifying the first cell. The wireless device may receive the packet on the first cell via radio resources identified by the downlink control information.

Abstract: An agent for managing virtual machines includes a persistent storage and an application agent manager. The persistent storage stores backup policies. The application agent manager identifies a new virtual machine instance and, in response to identifying the new virtual machine instance, performs proxy agent based analysis of the new virtual machine instance to generate a data loss threat profile of the new virtual machine instance; remediates the new virtual machine instance by instantiating application agents for the new virtual machine instance based on the data loss threat profile and a portion of the backup policies associated with the new virtual machine instance; updates at least one of the backup policies based on the instantiated application agents; and performs an application backup session for the new virtual machine instance using the instantiated application agents.

Abstract: Various embodiments are generally directed to improving card security by providing a user a contactless card with no sensitive card information, such as card number, card verification value, and expiration date, printed thereon, and displaying the sensitive card information relative to the card in augmented reality (AR) based on successful NFC-based user authentication. According to examples, the NFC-based user authentication may be performed by one-tapping or single tapping the contactless card to user mobile device. One or more portions of the sensitive card information may be obfuscated to further enhance card security. Moreover, the user can interact with AR elements including the sensitive card information to perform various actions.

Abstract: A device and method for the destruction of commercial explosives, improvised explosive devices (IED) and military grade weapons, particularly weapons with fragmentary and shrapnel ejection during detonation. The device is a multi-layer blanket with an impermeable first outer layer made of plastic or similar fiber. A blasting mat is located adjacent to the impermeable outermost layer for the containment of fragmentary and shrapnel ejection, should a detonation occur. One or more neutralization reagents are located between the blasting mat layer and a second, water-soluble seal, acting as an opposing outer layer. The versatile neutralization reagent(s) are released and rapidly react with the explosive fillers of breached munitions and similar devices when the water-soluble seal contacts water, while the outermost plastic layer isolates the neutralization reagents against the explosive item during the neutralization process and the blast mat provides protection in the event of an unexpected detonation.

Abstract: The present development is a device for monitoring uterine activity and sending an alert signal through a wireless communication means when uterine activity significantly changes relative to a preset standard. The device, which comprises at least one sensor, is intended to continuously monitor a prescribed activity, such as uterine contractions. The information gathered by the sensors is fed to a computer application for comparison to preset values and, if the gathered information falls outside of the range of the preset values, feeds a signal to a second application designed to send out notifications to preprogrammed devices indicating the physical location of the source data, or where the pregnant patient is located.

Abstract: A method in an electronic device, the method includes projecting infrared (“IR”) light from a plurality of light emitting diodes (“LEDs”) disposed proximate to the perimeter of the electronic device, detecting, by a sensor, IR light originating from at least two of the plurality of LEDs reflected from off of a person, and carrying out a function based on the relative strength of the detected IR light from the LEDs.

Abstract: Methods and devices are provided for promoting wound healing. In general, surgical staplers and staple components are provided having an effective amount of at least matrix metalloproteinase (MMP) inhibitor being effective to prevent MMP-mediated extracellular matrix degeneration during wound healing in tissue.

Abstract: The present disclosure is directed to systems and methods of facilitating a seismic survey and locating seismic data acquisition units in a marine environment. The system can include a first seismic data acquisition unit. The first seismic data can include a cleat ring to couple the first seismic data acquisition with a second seismic data acquisition unit. The system can include a rope having a first end coupled to a first portion of the first seismic data acquisition unit and a second end coupled to a second portion of the first seismic data acquisition unit. The system can include a cavity formed by the cleat ring. The system can include a telltale component coupled to a portion of the rope. The rope and the telltale component can be stored in the cavity of the first seismic data acquisition unit.

Abstract: Systems and methods of the disclosure relate to selecting content using beacon identifiers. An indication of a location of a user device and a beacon identifier are received. The beacon identifier can correspond to a beacon at a retail location. A data structure storing attribute data associated with the beacon identifier can be accessed. The attribute data can be associated with a signal having a unique identifier of the user device. The signal can indicate the retail location having the beacon. A request for content for display on the user device can be received. A content item can be selected for display on the user device based on the attribute data. A reward value can be determined based on receiving an indication of user interaction with the content item and the attribute data used to select the content item.

Abstract: A method for uniquely authenticating a device provides for receiving a scoping request, allocating a scope ID responsive to the request, and storing one or more device identification credentials in a database. Each device identification credential stored in the database includes the allocated scope ID and a device ID provided within the scoping request. The method further provides for receiving a registration request specifying a device identification credential and authenticating the specified device identification credential by confirming a match between the specified device identification credential and one of the device identification credentials stored in the database. The method further provides for provisioning the device with initial configuration information responsive to the authentication.

Abstract: A computer-implemented technique is described herein for facilitating discovery of information items. The technique involves providing at least one set of indicators to a user via a user interface presentation. The indicators represent respective topics. Each distance d between a pair of respective indicators, associated with respective topics (t, t?), is based on at least: a similarity between the topic t and the topic t? as expressed by a knowledge graph; and a dynamic and personalized joint measure of the user's current interest in the topic t and the topic t?. The technique further involves providing at least one information item to the user in response to the user's engagement with the user interface presentation.