Abstract: Disclosed are compounds of formula (I): and pharmaceutically acceptable salts thereof. The compounds of the invention are BDII-selective inhibitors of BET proteins, and have therapeutic potential for treating cancer, acute kidney disease, and viral infections, among other diseases.

Abstract: A communication system includes a plurality of repeater devices arranged at a plurality of different locations and are communicatively coupled over wired mediums. A first repeater device of the plurality of repeater devices obtains mmWave radio frequency (RF) and communicates, over a wired medium, the mmWave RF signal of the specified frequency to a second repeater device. The second repeater device extracts a plurality of different RF signals, corresponding to different communication protocols, from the mmWave RF signal and down-converts the extracted plurality of different RF signals. The second repeater device wirelessly distributes, from the mmWave RF signal, two or more different RF signals to end-user devices, packs content received from the end-user devices, and transmits upstream in the mmWave RF signal to the communication device via the first repeater device.

Abstract: A computing apparatus includes a hardware platform having a processor and a memory; an operating system (OS) having a GUI with a user-initiatable share function, and an interface to register a share target for the share function; and instructions encoded within the memory to provide a security agent, the instructions to instruct the processor to: receive from the OS a notification that an object has been shared to the security agent via the share function; responsive to the notification, initiate a security scan or reputation action for the shared object; receive a security or reputation response from the security scan or reputation action; and based at least in part on the security scan or reputation response, display a security or reputation notification via the GUI.

Abstract: Techniques for providing eyewear with electrical components are disclosed. The electrical components can provide electrical technology to eyewear (e.g., eyeglasses) without having to substantially compromise aesthetic design principles of the eyewear. The electrical components can operate independently or together with other electrical components provided elsewhere. The eyewear with electronic components can, for example, provide wireless communication, data capture, and/or audio output.

Abstract: A computer-aided method of educating a plurality of music students in an ensemble, including: (i) receiving search parameters from a client device for searching a multidimensional database of songs, the multidimensional database of songs being compiled to include dimensions of at least (a) instrument parts which indicate a music component being played by a particular type of instrument, (b) educational concepts present, (c) one or more proficiency levels for each of the instrument parts; (ii) searching the multidimensional database of songs to retrieve one or more songs that match the received search parameters, the one or more songs being songs that match proficiency levels of the plurality of music students in the ensemble; (iii) receiving an indication from the client device of a selected song in the one or more songs; and (iv) providing to the client device method books associated with educational concepts of the selected song.

Abstract: A vapor-generating system includes a cartridge, a vapor-generating device and a piercing element. The cartridge includes a cartridge housing configured to hold a solid vapor-forming substrate within the cartridge housing interior, a liquid storage housing configured to hold a liquid vapor-forming substrate within the liquid storage housing interior, and a frangible seal on the liquid storage housing. The vapor-generating device includes a device housing at least partially defining a cavity, an electric heater, and a power supply. The piercing element is configured to pierce the frangible seal of the cartridge to expose the liquid storage housing interior to be in fluid communication with the electric heater based on the vapor-generating device coupling with the cartridge such that the device housing at least partially receives the cartridge into the cavity. The electric heater is located externally from the piercing element.

Abstract: Various arrangements for performing wireless device-to-device communication are presented. An audio output device, such as an earbud or pair of earbuds, can establish a connection with an audio source via a first Bluetooth interface that communicates using a Bluetooth communication protocol on a 2.4 GHz Bluetooth frequency band. The audio output device can negotiate that Bluetooth frequency-shifted communication, such as on a 5 or 6 GHz frequency band, is available for use with the audio source. The audio output device may then perform Bluetooth frequency-shifted communication with the audio source such that the audio output device receives an audio stream from the audio source using Bluetooth frequency-shifted communication and the Bluetooth communication protocol.

Abstract: A baseboard element including a nose portion, a riser portion coupled to the nose portion, and a wall groove portion coupled to the riser portion. The nose portion includes a nose bottom section and a nose face section. The riser portion includes a riser section approximately perpendicular to the nose bottom section. The nose portion is positioned only on a first side of the riser section, and the wall groove portion is positioned only on a second side of the riser section, the second side opposite the first side. The nose bottom section comprises a nose bottom edge that is located at a terminal end of the nose bottom section and that is located closer to a plane defined by the riser section than the nose face section is to the plane. Other embodiments are also provided.

Abstract: A maintenance access system for a storage and retrieval system having a storage and retrieval space and automated transport vehicles disposed in the space. The system includes at least one maintenance access control unit associated with a portion of the space, at least one barrier in the space and defining a boundary of the portion of the space and configured to substantially prevent the passage of the vehicles past the at least one barrier, and a controller connected to the control unit, the controller being configured to receive a signal from the at least one control unit for isolating the portion of the space associated with the at least one control unit, where the controller in response to the signal closes the at least one barrier isolating the portion of the space and effects the removal from or shutting down of vehicles within the portion of the space.

Abstract: A system comprises a plurality of manifolds configured to combine a liquid and a gas into liquid-gas mixtures and deliver the liquid-gas mixtures to wells to facilitate product flow. Different manifolds of the plurality of manifolds operate on different parameters—e.g., produce liquid-gas mixtures having different compositions of liquid and gas—based on characteristics of the respective well associated with the respective manifold. An external liquid pump and/or gas compressor delivers liquid and/or gas to each manifold of the plurality of manifolds.

Abstract: A non-pressurized fluid reservoir for a vehicle coolant system includes a bottle configured to store fluid. The bottle has a neck defining an inner circumferential surface that is devoid of threads. The reservoir further includes a cap having a lid and a shank extending from the lid. The shank has an outer circumferential surface and with a spiral ramp supported on the outer circumferential surface to encircle a portion of the shank. The shank is receivable within the neck with the spiral ramp adjacent to the inner circumferential surface to mitigate fluid leaks through the neck.

Abstract: Methods, systems, and computer-readable medium are disclosed for presenting web application content. For example, a computer-readable medium may include instructions executable by one or more processors to perform operations including: executing a parent application using a web browser, the parent application being a single page application configured to display a web page element in the web browser; identifying a child application requested by a user action; obtaining, from a server system, child application code of the identified child application, the child application code defining a micro-frontend in a first programming language; transpiling the child application code from the first programming language to a second programming language executable by the web browser, to obtain a transpiled child application code renderable by the web browser; and rendering the transpiled child application code so that the micro-frontend is displayed in the web browser.

Abstract: One example system comprises a light source configured to emit light. The system also comprises a waveguide configured to guide the emitted light from a first end of the waveguide toward a second end of the waveguide. The waveguide has an output surface between the first end and the second end. The system also comprises a plurality of mirrors including a first mirror and a second mirror. The first mirror reflects a first portion of the light toward the output surface. The second mirror reflects a second portion of the light toward the output surface. The first portion propagates out of the output surface toward a scene as a first transmitted light beam. The second portion propagates out of the output surface toward the scene as a second transmitted light beam.

Abstract: The description relates to hinged devices, such as hinged computing devices. One example can include a first portion including an electronic component and a second portion including a second electronic component. A hinge assembly can rotatably secure the first and second portions through a range of rotation from a closed orientation to an open orientation. A dumbbell-shaped shield assembly can be configured to provide an orientation-specific protective pathway between the first portion and the second portion for a conductor extending from the first electronic component to the second electronic component.

Abstract: Embodiments provide a compact vertiport system. The vertiport system may be efficient and compact by combining, into one space and time period, multiple activities that typically take place in different spaces and different times. For example, when an aircraft is being moved from a landing zone to a takeoff zone, the aircraft may also be charged simultaneously. Also, passenger exchange may take place while the aircraft is being moved. As a result, compact vertiport systems may fit into smaller spaces (e.g., tops of buildings, or smaller plots of land).

Abstract: A control attachment configured to provide power to a load is described. The control attachment comprises a first plurality of contact elements; a plurality of openings on a first surface and having a second plurality of contact elements configured to receive a power signal and a neutral signal, wherein the plurality of openings are adapted to receive prongs of a plug; and a transformer coupled to receive the power signal and generate a low voltage signal; wherein the second plurality of contact elements is coupled to the first plurality of contact elements.

Abstract: Systems, devices, and methods are described for reducing degradation of a voice recognition input. An always listening device may always be listening for voice commands via a microphone and may experience interference from unwanted audio such as from the output audio of television speakers. The always listening device may receive data associated with the output audio over a first communications channel. The always listening device may also receive, on a second communications channel, timing information associated with data. The always listening device may adjust admission of the audio received by the microphone to enable it to arrive at approximately the same time as the data received via the first communications channel. The unwanted output audio included in the audio received via the microphone may then be determined and may be removed so that a voice command in the audio received by the microphone may be processed.

Abstract: Tracking controller configuration is provided. Each ECU of a plurality of ECUs is queried for feature codes indicative of elements of functionality implemented by the respective ECU. Each of the feature codes corresponds to a target quantity of ECUs involved in implementing the functionality. An alert is indicated responsive to the querying returning a different quantity of ECUs implementing the functionality than the target quantity.

Abstract: A method of training a speech model includes receiving, at a voice-enabled device, a fixed set of training utterances where each training utterance in the fixed set of training utterances includes a transcription paired with a speech representation of the corresponding training utterance. The method also includes sampling noisy audio data from an environment of the voice-enabled device. For each training utterance in the fixed set of training utterances, the method further includes augmenting, using the noisy audio data sampled from the environment of the voice-enabled device, the speech representation of the corresponding training utterance to generate noisy audio samples and pairing each of the noisy audio samples with the corresponding transcription of the corresponding training utterance. The method additionally includes training a speech model on the noisy audio samples generated for each speech representation in the fixed set of training utterances.

Abstract: A method includes receiving follow-on audio data captured by an assistant-enabled device, the follow-on audio data corresponding to a follow-on query spoken by a user of the assistant-enabled device to a digital assistant subsequent to the user submitting a previous query to the digital assistant. The method also includes processing, using a speech recognizer, the follow-on audio data to generate multiple candidate hypotheses, each candidate hypothesis corresponding to a candidate transcription for the follow-on query and represented by a respective sequence of hypothesized terms. For each corresponding candidate hypothesis among the multiple candidate hypotheses, the method also includes determining a corresponding similarity metric between the previous query and the corresponding candidate hypothesis and determining a transcription of the follow-on query spoken by the user based on the similarity metrics determined for the multiple candidate hypotheses.