Patents Assigned to LOCATE THERAPEUTICS LIMITED
  • Publication number: 20210290818
    Abstract: The invention relates to a method of forming a tissue scaffold material for controlled release of an agent in situ, or tissue regeneration, and a system of controlling scaffold and scaffold setting properties using various constituents, such as ceramics and/or plasticisers, and carriers. The invention further relates to scaffold material, scaffolds, and kits, and the use of such scaffold material and scaffolds in methods of treatment.
    Type: Application
    Filed: November 13, 2020
    Publication date: September 23, 2021
    Applicant: LOCATE THERAPEUTICS LIMITED
    Inventors: Antonio LEONARDI, Helen C. COX, Siobhan CAREY, Charles MATTHEWS, Alexander LOMAS, Kevin M. SHAKESHEFF, Robin A. QUIRK
  • Patent number: 10933167
    Abstract: A composition comprising polymer particles and a carrier, wherein the polymer particles are a mixture of at least a first polymer and a second polymer, wherein the first polymer is at least partially soluble or dispersible in the carrier, and wherein the polymer particles are arranged such that they can join together to form a scaffold of polymer particles, and wherein the composition is administrable to a human or non-human animal.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: March 2, 2021
    Assignee: LOCATE THERAPEUTICS LIMITED
    Inventors: Patrick Ginty, Robin Andrew Quirk, Kevin Morris Shakesheff
  • Publication number: 20200368387
    Abstract: The invention relates to a scaffold material composition for forming a solid tissue scaffold, the composition comprising a plurality of hollow polymer pellets, each pellet comprising an open hollow extending through the pellet, and wherein the plurality of hollow polymer pellets are capable of interlinking and setting into a solid scaffold. The invention further relates to associated compositions, uses, method of treatment and kits associated with such material.
    Type: Application
    Filed: February 12, 2018
    Publication date: November 26, 2020
    Applicant: Locate Therapeutics Limited
    Inventors: Antonio LEONARDI, Helen Celia COX, Robin Andrew Quirk, Kevin Morris Shakesheff
  • Publication number: 20200093956
    Abstract: The invention relates to a method of forming a tissue scaffold material for controlled release of an agent in situ, or tissue regeneration, and a system of controlling scaffold and scaffold setting properties using various constituents, such as ceramics and/or plasticisers, and carriers. The invention further relates to scaffold material, scaffolds, and kits, and the use of such scaffold material and scaffolds in methods of treatment.
    Type: Application
    Filed: March 23, 2017
    Publication date: March 26, 2020
    Applicant: LOCATE THERAPEUTICS LIMITED
    Inventors: Antonio LEONARDI, Helen C. COX, Siobhan CAREY, Charles MATTHEWS, Alexander LOMAS, Kevin M. SHAKESHEFF, Robin A. QUIRK
  • Patent number: 10232087
    Abstract: A porous matrix suitable for use as a tissue scaffold is described. The matrix may be shaped before insertion into or at the target tissue site, or injected via a minimally invasive method. The matrix may be pre-seeded with cells of the target tissue or may be used to support growth of the local endogenous tissue. The matrix may contain growth factors or other pharmacologically acceptable moieties such as antibiotics.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: March 19, 2019
    Assignee: LOCATE THERAPEUTICS LIMITED
    Inventors: Richard Melville France, Robin Andrew Quirk
  • Patent number: 10195309
    Abstract: A composition comprising polymer particles and a carrier, wherein the polymer particles are a mixture of at least a first polymer and a second polymer, wherein the first polymer is at least partially soluble or dispersible in the carrier, and wherein the polymer particles are arranged such that they can join together to form a scaffold of polymer particles, and wherein the composition is administrable to a human or non-human animal.
    Type: Grant
    Filed: February 1, 2008
    Date of Patent: February 5, 2019
    Assignee: LOCATE THERAPEUTICS LIMITED
    Inventors: Patrick Ginty, Robin Andrew Quirk, Kevin Morris Shakesheff
  • Patent number: 10086113
    Abstract: A porous matrix suitable for use as a tissue scaffold is described. The matrix may be shaped before insertion into or at the target tissue site, or injected via a minimally invasive method. The matrix may be pre-seeded with cells of the target tissue or may be used to support growth of the local endogenous tissue. The matrix may contain growth factors or other pharmacologically acceptable moieties such as antibiotics.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: October 2, 2018
    Assignee: LOCATE THERAPEUTICS LIMITED
    Inventors: Richard Melville France, Robin Andrew Quirk
  • Patent number: 9486558
    Abstract: A porous matrix suitable for use as a tissue scaffold is described. The matrix may be shaped before insertion into or at the target tissue site, or injected via a minimally invasive method. The matrix may be pre-seeded with cells of the target tissue or may be used to support growth of the local endogenous tissue. The matrix may contain growth factors or other pharmacologically acceptable moieties such as antibiotics.
    Type: Grant
    Filed: May 8, 2008
    Date of Patent: November 8, 2016
    Assignee: LOCATE THERAPEUTICS LIMITED
    Inventors: Richard Melville France, Robin Andrew Quirk
  • Publication number: 20160175482
    Abstract: An injectable agent delivery system comprising a composition that comprises: an agent for sustained delivery located within discrete particles; and an injectable scaffold material comprising discrete particles which are capable of interacting to form a scaffold, and uses thereof.
    Type: Application
    Filed: August 8, 2014
    Publication date: June 23, 2016
    Applicant: LOCATE THERAPEUTICS LIMITED
    Inventors: Robin Andrew QUIRK, Helen Celia COX, Kevin Morris SHAKESHEFF