Patents Assigned to LOGOS BIOSYSTEMS, INC.
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Patent number: 10443027Abstract: An apparatus for clearing tissue using electrophoresis according to an embodiment of the present invention comprises: a chamber which can contain therein a buffer solution and the biological tissue and has an inlet port and an outlet port for circulating the buffer solution; a support member, located within the chamber, for supporting the biological tissue; and electrodes located within the chamber and formed separately of a first electrode and a second electrode which correspond to each other. With the apparatus, it is possible to minimize the degradation of decomposition efficiency and quickly clear the tissue compared to a conventional apparatus.Type: GrantFiled: January 9, 2017Date of Patent: October 15, 2019Assignee: LOGOS BIOSYSTEMS, INC.Inventors: Keun Chang Cho, Neon Cheol Jung
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Publication number: 20180291420Abstract: The present invention relates to a method capable of detecting, identifying or counting microorganisms, and a system using the same, and provides a method capable of identifying, detecting or counting microorganisms in a more rapid, accurate and convenient manner than a conventional method for identifying, detecting or counting microorganisms. According to the present invention, it was found that identification, detection or counting of microorganisms can be performed in a rapid, accurate and convenient manner, when a fluorescently labeled microorganism sample is centrifuged and attached to the surface of a slide, followed by analysis of fluorescent images. Therefore, the method and system of the present invention can be useful in various fields requiring detection, identification and counting of microorganisms.Type: ApplicationFiled: April 30, 2016Publication date: October 11, 2018Applicant: LOGOS Biosystems, Inc.Inventors: Neoncheol JUNG, Keunchang CHO
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Patent number: 9046489Abstract: An excitation light from a first light source is adapted to be irradiated to a subject without passing through an objective lens so that the first light source and the subject may be arranged to be adjacent to each other. As a result, an excitation light having a high intensity of radiation may be irradiated to the subject to obtain a strong fluorescence signal. In addition, since the optical path of the excitation light from the first light source and the optical path of the fluorescent emission light emitted from the first dichroic mirror and the white light do not coincide with each other, a high S/N ratio may be obtained.Type: GrantFiled: March 25, 2014Date of Patent: June 2, 2015Assignee: LOGOS BIOSYSTEMS, INC.Inventors: Hyun Chang Lim, Neon Cheol Jung, Keun Chang Cho
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Publication number: 20140291547Abstract: An excitation light from a first light source is adapted to be irradiated to a subject without passing through an objective lens so that the first light source and the subject may be arranged to be adjacent to each other. As a result, an excitation light having a high intensity of radiation may be irradiated to the subject to obtain a strong fluorescence signal. In addition, since the optical path of the excitation light from the first light source and the optical path of the fluorescent emission light emitted from the first dichroic mirror and the white light do not coincide with each other, a high S/N ratio may be obtained.Type: ApplicationFiled: March 25, 2014Publication date: October 2, 2014Applicant: Logos Biosystems, Inc.Inventors: Hyun Chang LIM, Neon Cheol JUNG, Keun Chang CHO
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Patent number: 8808642Abstract: Disclosed is a microchip. The microchip of the present invention is characterized by comprising: a first plate; and a second plate coupled to the first plate to form a channel, wherein the first plate comprises: a channel cover part; a first connection part spaced apart from the outer periphery of the channel cover part by a certain distance; and a tensile strength generation connecting part for mutually connecting the channel cover part and the first connection part so that the channel cover part elastically contacts the channel region formed on the second plate when the first plate is coupled to the second plate. According to the present invention, the channel cover part forming the channel elastically contacts the channel region formed on the second plate, thereby providing a microchip capable of providing a channel having a stable structure.Type: GrantFiled: November 18, 2011Date of Patent: August 19, 2014Assignee: Logos Biosystems, Inc.Inventors: Hyun Chang Lim, Neon Cheol Jung, Keun Chang Cho
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Publication number: 20140178267Abstract: Disclosed is a microchip. The microchip of the present invention is characterized by comprising: a first plate; and a second plate coupled to the first plate to form a channel, wherein the first plate comprises: a channel cover part; a first connection part spaced apart from the outer periphery of the channel cover part by a certain distance; and a tensile strength generation connecting part for mutually connecting the channel cover part and the first connection part so that the channel cover part elastically contacts the channel region formed on the second plate when the first plate is coupled to the second plate. According to the present invention, the channel cover part forming the channel elastically contacts the channel region formed on the second plate, thereby providing a microchip capable of providing a channel having a stable structure.Type: ApplicationFiled: November 18, 2011Publication date: June 26, 2014Applicant: LOGOS BIOSYSTEMS, INC.Inventors: Hyun Chang Lim, Neon Cheol Jung, Keun Chang Cho
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Publication number: 20130147940Abstract: A cell counter includes: a sample slide configured to accommodate cells; a housing configured to be inserted into the inside of the sample slide from the outside of the sample slide; an object lens configured to be mounted within the housing, and to image-form a cell image for the cells projected from the sample slide; an image acquisition unit configured to be mounted within the housing together with the object lens, and to acquire the cell image image-formed by the object lens; and a first reflecting mirror provided between the sample slide and the object lens within the housing, and configured to change a projection direction of the cell image projected from the sample slide to the object lens.Type: ApplicationFiled: December 10, 2012Publication date: June 13, 2013Applicant: Logos Biosystems, Inc.Inventor: Logos Biosystems, Inc.
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Publication number: 20120258440Abstract: A method of deciding detachment time of cells, and a method and apparatus for subculturing the cells using the method. The method of deciding detachment time of the cells from a culturing vessel using a separation enzyme in subculturing the cells includes: a photographing step of photographing an image of the cells treated with the enzyme; a computing step of calculating a contrast value of the photographed image, and computing a change rate of the contrast value; a comparison step of repeating the photographing step and the computing step until an increasing change rate of the contrast value is reduced to a predetermined change rate or less; and a reporting step of reporting a time to remove the enzyme from the cells and to detach the cells from the culturing vessel when the increasing change rate of the contrast value is reduced to the predetermined change rate or less.Type: ApplicationFiled: April 5, 2012Publication date: October 11, 2012Applicant: LOGOS BIOSYSTEMS, INC.Inventors: Neon Cheol Jung, Keunchang Cho
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Publication number: 20110235169Abstract: Disclosed is a microscope module. The microscope module includes an objective lens magnifying an image of a sample subject for observation; an observation part for observing the image of the sample magnified through the objective lens; and a reflective mirror provided between the objective lens and the sample such that the vertical distance between the sample and the objective lens is substantially reduced. Since the reflective lens is disposed between the objective lens and the observation part, the working distance from the sample to the objective lens is substantially reduced, so that the height of the microscope is remarkably reduced. Thus, the microscope may be used in a place with vertical spatial limitations.Type: ApplicationFiled: March 9, 2011Publication date: September 29, 2011Applicant: LOGOS BIOSYSTEMS, INC.Inventors: Hyun Chang LIM, Neon Cheol JUNG, Keun Chang CHO