Patents Assigned to Lonza Bend Inc.
  • MIXED SOLVENTS FOR SPRAY DRYING FOR PREPARATION OF AMORPHOUS SOLID DISPERSIONS
    Publication number: 20240277620
    Abstract: A method for preparing an amorphous solid dispersion by spray drying a spray solution comprising a) a mixed solvent, the mixed solvent comprising i. a solvent 1 selected from the group consisting of methyl acetate, methyl formate, ethyl acetate, ethyl formate and mixtures thereof; ii.
    Type: Application
    Filed: June 8, 2022
    Publication date: August 22, 2024
    Applicant: Lonza Bend Inc.
    Inventors: Warren Miller, Molly Adam, Michael Morgen, John Baumann
  • SPRAY DRYING OF API IN SUPERSATURATED SOLUTIONS WITH FORMIC ACID
    Publication number: 20240277619
    Abstract: The invention discloses a method for preparation of spray dried solid dispersions (SDD) comprising an active pharmaceutical ingredient (API) and a dispersion polymer (DISPPOL), wherein the spray drying is done with a supersaturated solution of API in a solvent mixture comprising two solvents, this supersaturated solution further comprising DISPPOL.
    Type: Application
    Filed: June 9, 2022
    Publication date: August 22, 2024
    Applicant: Lonza Bend Inc.
    Inventors: Michael Morgen, Molly Adam, John Baumann, Nathan Bennette, Michael Grass, Warren Miller, Amanda Pluntze, Daniel Regan, David Vodak
  • FORMIC ACID AS PROCESSING AID IN SPRAY DRYING FOR BASIC DRUGS
    Publication number: 20240261225
    Abstract: The invention discloses a method for preparation of spray dried solid dispersions, SDD, comprising an active agent, AA, such as an active pharmaceutical ingredient, API, and a dispersion polymer, DISPPOL, wherein the spray drying is done with a solution of AA and of DISPPOL in a solvent comprising C1-3 alkanol and formic acid, and optionally water.
    Type: Application
    Filed: June 3, 2022
    Publication date: August 8, 2024
    Applicant: Lonza Bend Inc.
    Inventors: Michael Morgen, Warren Miller, David Vodak, Jonathan Cape, Molly Adam, Michael Grass
  • INHALABLE DRY POWDER FORMULATIONS COMPRISING ANGIOGENESIS INHIBITORS
    Publication number: 20240197628
    Abstract: The present disclosure relates to inhalable dry powder formulations comprising one or more antibodies or one or more angiogenesis inhibiting active pharmaceutical ingredients, methods of manufacture of such compositions, e.g., via spray drying, as well as their local administration to the lung for use in the treatment, prevention and/or delay of progression of asthma, COPD, lung infections, cystic fibrosis, or lung cancer.
    Type: Application
    Filed: February 28, 2024
    Publication date: June 20, 2024
    Applicant: Lonza Bend Inc.
    Inventors: Kimberly Shepard, Michael Banks, David Vodak
  • INHALABLE DRY POWDER FORMULATIONS COMPRISING ANGIOGENESIS INHIBITORS
    Publication number: 20240000707
    Abstract: The present invention relates to inhalable dry powder formulations comprising one or more antibodies or one or more angiogenesis inhibiting active pharmaceutical ingredients, methods of manufacture of such compositions, e.g. via spray drying, as well as their local administration to the lung for use in the treatment, prevention and/or delay of progression of asthma, COPD, lung infections, cystic fibrosis, or lung cancer.
    Type: Application
    Filed: November 17, 2021
    Publication date: January 4, 2024
    Applicant: Lonza Bend Inc.
    Inventors: Kimberly Shepard, Michael Banks, David Vodak
  • ACETIC ACID AS PROCESSING AID IN SPRAY DRYING FOR BASIC DRUGS
    Publication number: 20230414515
    Abstract: The invention discloses a method for preparation of spray dried solid dispersions, SDD, comprising an active agent, AA, such as an active pharmaceutical ingredient, API, and a dispersion polymer, DISPPOL, wherein the spray drying is done with a solution of AA and of DISPPOL in a solvent comprising C1-3 alkanol and acetic acid, and optionally water.
    Type: Application
    Filed: September 30, 2021
    Publication date: December 28, 2023
    Applicant: Lonza Bend Inc.
    Inventors: Michael Morgen, Warren Miller, David Vodak, Jonathan Cape, Molly Adam
  • SPRAY DRYING OF SUPERSATURATED SOLUTIONS OF API WITH ACETIC ACID
    Publication number: 20230293439
    Abstract: The invention discloses a method for preparation of spray dried solid dispersions (SDD) comprising an active pharmaceutical ingredient (API) and a dispersion polymer (DISPPOL), wherein the spray drying is done with a supersaturated solution of API in a solvent mixture comprising two solvents, one is acetic acid, this supersaturated solution further comprising DISPPOL.
    Type: Application
    Filed: July 22, 2021
    Publication date: September 21, 2023
    Applicant: Lonza Bend Inc.
    Inventors: Molly Adam, John Baumann, Nathan Bennette, Warren Miller, Michael Morgen, Amanda Pluntze, Daniel Regan, David Vodak