Patents Assigned to Los Alamos National Security, LLC
  • Patent number: 9434956
    Abstract: The invention relates to transgenic plants exhibiting dramatically enhanced growth rates, greater seed and fruit/pod yields, earlier and more productive flowering, more efficient nitrogen utilization, increased tolerance to high salt conditions, and increased biomass yields. In one embodiment, transgenic plants engineered to over-express both glutamine phenylpyruvate transaminase (GPT) and glutamine synthetase (GS) are provided. The GPT+GS double-transgenic plants of the invention consistently exhibit enhanced growth characteristics, with T0 generation lines showing an increase in biomass over wild type counterparts of between 50% and 300%. Generations that result from sexual crosses and/or selfing typically perform even better, with some of the double-transgenic plants achieving an astounding four-fold biomass increase over wild type plants.
    Type: Grant
    Filed: December 14, 2012
    Date of Patent: September 6, 2016
    Assignees: LOS ALAMOS NATIONAL SECURITY, LLC, UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEES
    Inventors: Pat J. Unkefer, Penelope S. Anderson, Thomas J. Knight
  • Patent number: 9434666
    Abstract: Complexes of cobalt and nickel with tridentate ligand PNHPR are effective for hydrogenation of unsaturated compounds. Cobalt complex [(PNHPCy)Co(CH2SiMe3)]BArF4 (PNHPCy=bis[2-(dicyclohexylphosphino)ethyl]amine, BArF4=B(3,5-(CF3)2C6H3)4)) was prepared and used with hydrogen for hydrogenation of alkenes, aldehydes, ketones, and imines under mild conditions (25-60° C., 1-4 atm H2). Nickel complex [(PNHPCy)Ni(H)]BPh4 was used for hydrogenation of styrene and 1-octene under mild conditions. (PNPCy)Ni(H) was used for hydrogenating alkenes.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: September 6, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Kalyan V. Vasudevan, Guoqi Zhang, Susan K. Hanson
  • Patent number: 9436722
    Abstract: Checksum values are generated and used to verify the data integrity. A client executing in a parallel computing system stores a data chunk to a shared data object on a storage node in the parallel computing system. The client determines a checksum value for the data chunk; and provides the checksum value with the data chunk to the storage node that stores the shared object. The data chunk can be stored on the storage node with the corresponding checksum value as part of the shared object. The storage node may be part of a Parallel Log-Structured File System (PLFS), and the client may comprise, for example, a Log-Structured File System client on a compute node or burst buffer. The checksum value can be evaluated when the data chunk is read from the storage node to verify the integrity of the data that is read.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 6, 2016
    Assignees: EMC Corporation, Los Alamos National Security, LLC
    Inventors: John M. Bent, Sorin Faibish, Gary Grider
  • Patent number: 9422207
    Abstract: The present invention is directed to the preparation of oxygenated, unsaturated hydrocarbon compounds, such as derivatives of furfural or hydroxymethyl furfural produced by aldol condensation with a ketone or a ketoester, as well as methods of deoxidatively reducing those compounds with hydrogen under acidic conditions to provide saturated hydrocarbons useful as fuels.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 23, 2016
    Assignees: Los Alamos National Security, LLC, The Proctor & Gamble Company
    Inventors: John Cameron Gordon, Louis A. Silks, Andrew D. Sutton, Ruilian Wu, Marcel Schlaf, Fraser Waldie, Ryan West, Dimitris Ioannis Collias
  • Patent number: 9425461
    Abstract: A process for rejuvenating fuel cells has been demonstrated to improve the performance of polymer exchange membrane fuel cells with platinum/ionomer electrodes. The process involves dehydrating a fuel cell and exposing at least the cathode of the fuel cell to dry gas (nitrogen, for example) at a temperature higher than the operating temperature of the fuel cell. The process may be used to prolong the operating lifetime of an automotive fuel cell.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: August 23, 2016
    Assignee: LOS ALAMOS NATIONAL SECURITY, LLC
    Inventors: Yu Seung Kim, David A. Langlois
  • Patent number: 9411031
    Abstract: Technologies related to identification of a substance in an optimized manner are provided. A reference group of known materials is identified. Each known material has known values for several classification parameters. The classification parameters comprise at least one of T1, T2, T1?, a relative nuclear susceptibility (RNS) of the substance, and an x-ray linear attenuation coefficient (LAC) of the substance. A measurement sequence is optimized based on at least one of a measurement cost of each of the classification parameters and an initial probability of each of the known materials in the reference group.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: August 9, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Michelle A. Espy, Andrei N. Matlashov, Larry J. Schultz, Petr L. Volegov
  • Patent number: 9409825
    Abstract: A mixture of fine powder including thorium oxide was converted to granulated powder by forming a first-green-body and heat treating the first-green-body at a high temperature to strengthen the first-green-body followed by granulation by crushing or milling the heat-treated first-green-body. The granulated powder was achieved by screening through a combination of sieves to achieve the desired granule size distribution. The granulated powder relies on the thermal bonding to maintain its shape and structure. The granulated powder contains no organic binder and can be stored in a radioactive or other extreme environment. The granulated powder was pressed and sintered to form a dense compact with a higher density and more uniform pore size distribution.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: August 9, 2016
    Assignee: Los Alamos National Security, LLC
    Inventor: Ching-Fong Chen
  • Patent number: 9404890
    Abstract: A method for determining the composition of fluids flowing through pipes from noninvasive measurements of acoustic properties of the fluid is described. The method includes exciting a first transducer located on the external surface of the pipe through which the fluid under investigation is flowing, to generate an ultrasound chirp signal, as opposed to conventional pulses. The chirp signal is received by a second transducer disposed on the external surface of the pipe opposing the location of the first transducer, from which the transit time through the fluid is determined and the sound speed of the ultrasound in the fluid is calculated. The composition of a fluid is calculated from the sound speed therein. The fluid density may also be derived from measurements of sound attenuation. Several signal processing approaches are described for extracting the transit time information from the data with the effects of the pipe wall having been subtracted.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: August 2, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Dipen N. Sinha, Curtis F. Osterhoudt, Anirban Chaudhuri
  • Publication number: 20160213772
    Abstract: Disclosed herein are mosaic conserved region HIV polypeptides and immunogenic polypeptides including one or more of the mosaic conserved region polypeptides. In some embodiments, the immunogenic polypeptides are included in an immunogenic composition, such as a polyvalent immunogenic composition. Also disclosed herein are methods for treating or inhibiting HIV in a subject including administering one or more of the disclosed immunogenic polypeptides or compositions to a subject having or at risk of HIV infection. In some embodiments, the methods include inducing an immune response in a subject comprising administering to the subject at least one of the disclosed immunogenic polypeptides or a nucleic acid encoding at least one of the immunogenic polypeptides.
    Type: Application
    Filed: September 30, 2014
    Publication date: July 28, 2016
    Applicants: Los Alamos National Security, LLC, Isis Innovation Limited
    Inventors: Bette T.M. Korber, Tomas Hanke, Andrew McMichael
  • Patent number: 9394917
    Abstract: Cooling devices for use with electric submersible pump motors include a refrigerator attached to the end of the electric submersible pump motor with the evaporator heat exchanger accepting all or a portion of the heat load from the motor. The cooling device can be a self-contained bolt-on unit, so that minimal design changes to existing motors are required.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: July 19, 2016
    Assignee: LOS ALAMOS NATIONAL SECURITY, LLC
    Inventors: Todd A. Jankowski, Dallas D. Hill
  • Patent number: 9388667
    Abstract: A method for heating a production fluid in a wellbore. The method can include heating, using a packer fluid, a working fluid flowing through a first medium disposed in a first section of the wellbore, where the first medium transfers heat from the packer fluid to the working fluid. The method can also include circulating the working fluid into a second section of the wellbore through a second medium, where the second medium transfers heat from the working fluid to the production fluid. The method can further include returning the working fluid to the first section of the wellbore through the first medium.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: July 12, 2016
    Assignees: CHEVRON U.S.A. INC., LOS ALAMOS NATIONAL SECURITY, LLC.
    Inventors: Yamila Orrego, Todd A. Jankowski
  • Patent number: 9382294
    Abstract: The discovery of a non-ribosomal peptide synthetase (NRPS) gene cluster in the genome of Clostridium thermocellum that produces a secondary metabolite that is assembled outside of the host membrane is described. Also described is the identification of homologous NRPS gene clusters from several additional microorganisms. The secondary metabolites produced by the NRPS gene clusters exhibit broad spectrum antibiotic activity. Thus, antibiotic compounds produced by the NRPS gene clusters, and analogs thereof, their use for inhibiting bacterial growth, and methods of making the antibiotic compounds are described.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: July 5, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Alexander Koglin, Matthias Strieker
  • Patent number: 9378310
    Abstract: A computer system and method of simulating the behavior of an oil and gas reservoir including changes in the margins of frangible solids. A system of equations including state equations such as momentum, and conservation laws such as mass conservation and volume fraction continuity, are defined and discretized for at least two phases in a modeled volume, one of which corresponds to frangible material. A material point model technique for numerically solving the system of discretized equations, to derive fluid flow at each of a plurality of mesh nodes in the modeled volume, and the velocity of at each of a plurality of particles representing the frangible material in the modeled volume. A time-splitting technique improves the computational efficiency of the simulation while maintaining accuracy on the deformation scale. The method can be applied to derive accurate upscaled model equations for larger volume scale simulations.
    Type: Grant
    Filed: October 11, 2012
    Date of Patent: June 28, 2016
    Assignees: Los Alamos National Security, LLC, BP Corporation North America Inc.
    Inventors: William Brian Vanderheyden, Duan Zhang
  • Patent number: 9374380
    Abstract: Non-harmful data mimicking computer network attacks may be inserted in a computer network. Anomalous real network connections may be generated between a plurality of computing systems in the network. Data mimicking an attack may also be generated. The generated data may be transmitted between the plurality of computing systems using the real network connections and measured to determine whether an attack is detected.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: June 21, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Joshua Charles Neil, Alexander Kent, Curtis Lee Hash, Jr.
  • Patent number: 9368311
    Abstract: A photocathode device may replenish its photoemissive coating to replace coating material that desorbs/evaporates during photoemission. A linear actuator system may regulate the release of a replenishment material vapor, such as an alkali metal, from a chamber inside the photocathode device to a porous cathode substrate. The replenishment material deposits on the inner surface of a porous membrane and effuses through the membrane to the outer surface, where it replenishes the photoemissive coating. The rate of replenishment of the photoemissive coating may be adjusted using the linear actuator system to regulate performance of the photocathode device during photoemission. Alternatively, the linear actuator system may adjust a plasma discharge gap between a cartridge containing replenishment material and a metal grid. A potential is applied between the cartridge and the grid, resulting in ejection of metal ions from the cartridge that similarly replenish the photoemissive coating.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: June 14, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Nathan A. Moody, David C. Lizon
  • Patent number: 9360573
    Abstract: A system and method of characterizing properties of a medium from a non-linear interaction are include generating, by first and second acoustic sources disposed on a surface of the medium on a first line, first and second acoustic waves. The first and second acoustic sources are controllable such that trajectories of the first and second acoustic waves intersect in a mixing zone within the medium. The method further includes receiving, by a receiver positioned in a plane containing the first and second acoustic sources, a third acoustic wave generated by a non-linear mixing process from the first and second acoustic waves in the mixing zone; and creating a first two-dimensional image of non-linear properties or a first ratio of compressional velocity and shear velocity, or both, of the medium in a first plane generally perpendicular to the surface and containing the first line, based on the received third acoustic wave.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: June 7, 2016
    Assignees: LOS ALAMOS NATIONAL SECURITY LLC, CHEVRON U.S.A. INC.
    Inventors: Cung Khac Vu, Kurt Toshimi Nihei, Paul A. Johnson, Robert A. Guyer, James A. Ten Cate, Pierre-Yves Le Bas, Carene S. Larmat
  • Patent number: 9359319
    Abstract: The ?,?-unsaturated ketone moiety of a substrate representative of non-food based biomass was hydrogenated to the corresponding saturated alcohol moiety using a composition including (1) a copper salt; (2) a phosphine; (3) a polar aprotic solvent such as acetonitrile, and (4) a compound suitable for providing hydrogen for the hydrogenation, such as a suitable silane material or a suitable siloxane material.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: June 7, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: John C. Gordon, Christopher R. Waidmann
  • Publication number: 20160153271
    Abstract: Explosive geologic fracturing methods, devices, and systems can be used in combination with other geologic fracturing means, such as hydraulic fracturing methods, devices and systems, or other fluid-based fracturing means. An exemplary method comprises introducing an explosive system into a wellbore in a geologic formation, detonating the explosive system in the wellbore to fracture at least a first portion of the geologic formation adjacent to the wellbore, and introducing pressurized fluid into the wellbore to enhance the fracturing of the first portion of the geologic formation. Such multi-stage fracturing can further enhance the resulting fracturing of a geologic formation relative to explosive fracturing alone.
    Type: Application
    Filed: July 15, 2014
    Publication date: June 2, 2016
    Applicant: Los Alamos National Security, LLC
    Inventors: Jonathan Lee Mace, Lawrence E. Bronisz, David W. Steedman, Christopher Robert Bradley
  • Patent number: 9354346
    Abstract: An acoustic source for generating an acoustic beam includes a housing; a plurality of spaced apart piezo-electric layers disposed within the housing; and a non-linear medium filling between the plurality of layers. Each of the plurality of piezoelectric layers is configured to generate an acoustic wave. The non-linear medium and the plurality of piezo-electric material layers have a matching impedance so as to enhance a transmission of the acoustic wave generated by each of plurality of layers through the remaining plurality of layers.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 31, 2016
    Assignees: LOS ALAMOS NATIONAL SECURITY, LLC, CHEVRON U.S.A. INC.
    Inventors: Cung Khac Vu, Dipen N. Sinha, Cristian Pantea
  • Patent number: 9353435
    Abstract: A process for stabilizing laser energy density on a target surface during pulsed laser deposition of thin films controls the focused laser spot on the target. The process involves imaging an image-aperture positioned in the beamline. This eliminates changes in the beam dimensions of the laser. A continuously variable attenuator located in between the output of the laser and the imaged image-aperture adjusts the energy to a desired level by running the laser in a “constant voltage” mode. The process provides reproducibility and controllability for deposition of electronic thin films by pulsed laser deposition.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: May 31, 2016
    Assignee: Los Alamos National Security, LLC
    Inventors: Paul C. Dowden, Quanxi Jia