Abstract: This invention provides novel compositions and methods for the specific and/or preferential delivery of an effector (e.g. a drug or label) to an epithelial cell (e.g. a pulmonary epithelium). The compositions comprise an adipocyte differentiation-related protein (ADRP) attached to an effector thereby forming a chimeric moiety. The chimeric moiety is preferentially delivered to epithelial cells.
Type:
Grant
Filed:
April 3, 2006
Date of Patent:
November 29, 2011
Assignee:
Los Angeles Biomedical Reseach Institute at Harbor UCLA Medical Center