Patents Assigned to Losec, Inc
  • Transplantable particulate bone composition having high osteoinductive capacity and methods for making and using same
    Patent number: 7335381
    Abstract: A particulate bone of defined sizes which has a unique property of direct bone osteoinduction without going through endochondral ossification stage is disclosed. The bone is not subjected to chemical extraction or decalcification. This allows for the retention of all physiologically active components of native bone. The invention hinges on the newly discovered ability of bone particles of defined sizes to exert osteoinduction by a pathway superior to and distinct from demineralized bone matrix and similar preparations.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: February 26, 2008
    Assignee: Losec, Inc
    Inventors: Theodore I. Malinin, H. Thomas Temple, Alvaro Flores, Billy E. Buck