Abstract: An embodiment of the present invention provides for a dry powder pharmaceutical composition suitable for dispersion in an aerosol for inhaled administration to a patient with cancer, the composition comprising: a cytidine analogue including salts, solvates, hydrates, and esters thereof; and a pharmaceutically acceptable excipient together forming the dry powder pharmaceutical composition suitable for dispersion in the aerosol for administration via inhalation to the patient with cancer. Another embodiment provides for a method of making the composition and a further embodiment provides for a method a treating a patient in need thereof with the composition.
Type:
Grant
Filed:
August 7, 2020
Date of Patent:
March 8, 2022
Assignee:
Lovelace Biomedical Research Institute
Inventors:
Steven A. Belinsky, Philip J. Kuehl, Aaron Badenoch, Michael Burke, Devon Dubose
Abstract: An embodiment of the present invention provides for a dry powder pharmaceutical composition suitable for dispersion in an aerosol for inhaled administration to a patient with cancer, the composition comprising: a cytidine analogue including salts, solvates, hydrates, and esters thereof; and a pharmaceutically acceptable excipient together forming the dry powder pharmaceutical composition suitable for dispersion in the aerosol for administration via inhalation to the patient with cancer. Another embodiment provides for a method of making the composition and a further embodiment provides for a method a treating a patient in need thereof with the composition.
Type:
Application
Filed:
August 7, 2020
Publication date:
November 26, 2020
Applicant:
Lovelace Biomedical Research Institute
Inventors:
Steven A. Belinsky, Philip J. Kuehl, Aaron Badenoch, Michael Burke, Devon Dubose