Abstract: A method of delivering a therapeutic substance to tissue comprises delivering the therapeutic substance and nanoparticles to the tissue, the nanoparticles having a diameter in the range from 10 to 1000 nm and surface features having a depth in the range from 5 to 50 nm, and insonating the tissue with pressure waves. Corresponding particles, and associated methods of controlling and imaging the treatment and delivery are also disclosed.
Type:
Application
Filed:
November 17, 2011
Publication date:
October 24, 2013
Applicant:
lsis Innovation Limited
Inventors:
Sarah Jayne Wagstaffe, Heiko Alexander Schiffter-Weinle, Michael Bernard Molinari, Manish Arora, Coussios Constantin-Cassios
Abstract: A method for producing a bilayer of amphipathic molecules comprising providing a hydrated support and providing a hydrophilic body, and bringing the hydrated support and hydrophilic body into contact to form a bilayer of amphipathic molecules. A bilayer produced by the method of the invention, and uses of the bilayer.