Abstract: A process for ascertaining the adhesive behaviour of pressure-sensitive adhesive flat materials such as medicinal adhesive tape and, in particular, pressure-sensitive adhesive application systems such as transdermal therapeutic systems (TTS) is characterized in that a flat material (5) with an adhesive layer (6) of a defined coating weight per unit area and of defined quality of the adhesive mass is adhered with predetermined surface pressure and at a predetermined temperature to an elastic carrier film (4) of defined thickness and elasticity, and that said carrier film (4) is clamped into a test cell (21), in the manner of a membrane, between half-shells (1,2) of a test cell (21), and that the carrier film (4) along with the adhered flat material (5) is subjected, in chronologically repeated sequence, to loading and unloading with alternating elastic stretchings by defined loading forces from the side facing away from the flat material, and that a detachment of the adhesive layer, which detachment arises pro

Abstract: A pharmaceutical preparation adhering to the skin, in particular a TTS, for the release of the active substance 17-&bgr;-estradiol, the concentration of the estradiol contained therein in dissolved form being between its saturation concentration in equilibrium with a gas phase of less than 10% relative air humidity and its saturation concentration in equilibrium with a gas phase of more than 90% relative air humidity, in all matrix layers and, if present, also in an adhesive layer, characterized in that the estradiol quantity contained in the preparation amounts to at least three times the saturation solubility measured at 95% relative air humidity, and that the air enclosed in the package is adjusted to a relative air humidity between 5% and below 0.5%.

Abstract: A tampon printing process which uses a printing plate having at least one printing form at its surface, wherein the printing form is filled with printing medium at time intervals and the printing medium is subsequently transferred from the printing form onto a support by means of a tampon.

Abstract: A transdermal therapeutic system (TTS) for the administration of galanthamine to the skin each system having a backing layer which is impermeable to active substances and a pressure sensitive adhesive reservoir layer, wherein the reservoir layer comprises 40-80% wt. polymeric material selected from the group consisting of polyacrylates, 0.1-30%-wt. plasticizers, and 0.1-30%-wt. galanthamine base or one of its pharmaceutically acceptable salts.