Abstract: The invention relates to a fixing system for fixing catheters, cannulas, etc. with a skin film (3) coated with a skin adhesion layer (2) and having a cover film (1) and an overplaster (6) finished with a pressure sensitive adhesive layer (5) adhering to the skin film and having an overplaster cover layer (4), as well as to a process for the sterile fastening of a cannula to the skin with the following steps: application of a bacteria-tight skin film with skin adhesion layer to the skin in the insertion region of the cannula, passing the cannula through the skin film, applying an adhesive forming an elastic, bacteria-tight film adhering to the skin film region surrounding the insertion point and the cannula portion projecting out of the skin and sticking the overplaster over the cannula.
Type:
Grant
Filed:
November 19, 1992
Date of Patent:
August 17, 1993
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Abstract: The present invention relates to a device for the release of systemic active substances to plants consisting of a backing layer and an active substance reservoir, which device is characterized in that the active substance reservoir is deformable and adaptable to uneven surfaces and that it is suitable for releasing active substances through surfaces of plants consisting of secondary, hardened superficial tissues not being covered by a cuticula.
Type:
Grant
Filed:
June 29, 1990
Date of Patent:
November 10, 1992
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Inventors:
Hans-Rainer Hoffmann, Jurgen Maass, Walter Muleer, Michael Roreger
Abstract: The present invention relates to a therapeutic system for the transdermal or transmucous administration of active substances via an impermeable backing layer, a reservoir which at least partially comprises active substance, is double-layered and consists of separate parts, and a protective layer, whereby the two reservoir members(a) are positioned substantially parallely on top of each other,(b) are separated from each other by a removable intermediate layer being impermeable to the active substances of said reservoir members,(c) either comprise active substance or auxiliary agents or both at concentrations not corresponding to the distribution equilibrium.
Type:
Grant
Filed:
February 6, 1990
Date of Patent:
July 7, 1992
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Inventors:
Walter Muller, Michael Roreger, Heinrich Kindel, Peter Bohnenkamper, Heike Palm
Abstract: In combination, a bag, at least one active mass, and a support, the active mass being carried on the support within the bag and having an exposed pressure-sensitive adherent surface, the support carrying integral spacers which are laterally spaced from the active mass and project above the surface of the support a distance greater than the height of said active mass, thereby to space the mass from the bag.
Type:
Grant
Filed:
June 26, 1990
Date of Patent:
May 26, 1992
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Abstract: The invention relates to a process for producing an administration and/or dosage form for medicament active substances using a printing process, in which the printing process used is a pad printing process.
Type:
Grant
Filed:
August 13, 1991
Date of Patent:
May 5, 1992
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Abstract: The present invention relates to a process for the visualization of substance stains on dry layer chromatograms without further addition of a mobile phase, which device has foil of at least one layer and comprises one or more reagents for the visualization of substance stains.
Type:
Grant
Filed:
June 27, 1991
Date of Patent:
April 21, 1992
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Abstract: The invention relates to a removal aid for mechanically detachable substrates adhering to a sheet-like, flexible carrier material and in the form of cuts or predetermined breaking lines in said carrier material. At least in the contact surface of the carrier material is provided for each substrate a separate, non-linear cutting or predetermined breaking line, so that when pressure is exerted on the carrier material with a force component in a direction at right angles to the substrate contact surface a carrier material portion with the substrate portion adhering thereto and bounded by the cutting or predetermined breaking line can be bent in the direction of the substrate or substrates, so that at least part of the substrate in the border area thereof adjacent to the cutting or predetermined breaking line is detached from the carrier material and consequently a gripping portion is formed on the substrate for the complete removal of the latter.
Type:
Grant
Filed:
November 8, 1990
Date of Patent:
February 25, 1992
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Abstract: The present invention relates to a transdermal therapeutical system for the administration of physostigmine to the skin via a cover layer which is impermeable to active substances, a pressure-sensitive adhesive reservoir layer, and optionally a removable protective layer, said reservoir layer consisting of 10-90% polymeric material selected from the groups consisting of block copolymers on the basis of styrene and 1,3-dienes, polyisobutylenes, polymers on the basis of acrylates and/or methacrylates and esters of hydrogenated colophonium, 0-30%-wt softeners on the basis of hydrocarbons and/or esters, and 0.1-20%-wt physostigmine.
Abstract: The present invention relates to a superficial therapeutic system consisting of an impermeable backing layer, an active substance containing matrix, and a removable protective layer, in which the matrix comprises:a. antineoplastic active substanceb. a self-adhesive polyacrylatec. a water absorberand optionallyd. a non-adhesive hydrophilic polyacrylatee. a softener and/or penetration accelerator.
Type:
Grant
Filed:
January 19, 1990
Date of Patent:
December 31, 1991
Assignee:
LTS Lohmann Therapie-Systeme GmbH & Co. KG
Abstract: The invention relates to a transdermal therapeutic system for administering or applying active substances to the skin with a backing layer remote from the skin, an active substance depot, an active substance delivery control means controlling the delivery of the active substance through the system and a contact adhesive means for fixing the therapeutic system to the skin, in which the active substance depot is a multichamber system, in which discreet chambers contain one or more active substances.
Type:
Grant
Filed:
April 3, 1989
Date of Patent:
November 19, 1991
Assignee:
Lts Lohmann Therapie-Systeme GmbH & Co. KG