Abstract: The present invention relates to the use of CDK8 and/or CDK19 inhibitors in the treatment of ribosomopathies as well as conditions characterized by reduced number of hematopoietic stem cells and/or progenitor cells; and bone anabolic disorders.

Abstract: The present invention relates to methods and tools for discriminating between Vel negative and Vel positive phenotypes. The invention is thus useful for determining Vel blood group status of individuals about to receive blood transfusion.

Abstract: The present invention relates to methods and tools for discriminating between Vel negative and Vel positive phenotypes. The invention is thus useful for determining Vel blood group status of individuals about to receive blood transfusion.

Abstract: The invention relates to a compression device (1) for assisting x-ray examination of an object. The compression device (1) comprises a support plate (3) adapted to receive thereon the object to be examined; a compression plate (4); and a displacement device (5) arranged to interact with the support plate (3) and the compression plate (4) to allow modification of the spacing (A) between the support plate (3) and the compression plate (4) to compress the object there between. A plurality of pressure sensors (13) are distributed across the support plate (3) and/or the compression plate (4) for sensing local pressure distribution across the compression area of the compressed object. The displacement device (1) is arranged to set and adapt the spacing (A) between the support plate (3) and the compression plate (4) angularly and linearly as a result of the sensed local pressure distribution across the compression area.