Patents Assigned to Lucerno Dynamics, LLC
  • Patent number: 12061298
    Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte is presented. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system utilizes computer program code executable by a computer processor that performs the steps of receiving signal data, accessing reference data, and comparing the signal data to the reference data to determine a likelihood of improper administration of the radioactive analyte to the subject.
    Type: Grant
    Filed: May 2, 2023
    Date of Patent: August 13, 2024
    Assignee: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze, Steve Perrin
  • Patent number: 11963808
    Abstract: Various embodiments of a device for in-vivo measurements radiopharmaceuticals used for diagnosis and monitoring of radiotherapy are presented. In some embodiments, the present disclosure relates to a device having a cannula that may include a measurement chamber, a radiation detector and a delivery lumen, wherein the device may be used to both deliver material to the patient (e.g., radiotracers used in radiopharmaceuticals) and measure levels and concentrations of radioactive material in, for example, the patient's blood both during and after administration of the radioactive material. In some embodiments, particles emitted by the radioactive material interact with a scintillation material, resulting in the release of light that may be transmitted, via the scintillation material and/or fiber optic material, to an optical detectors or processor for processing.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: April 23, 2024
    Assignee: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Ronald K. Lattanze, Paul Mozley, Steven Perrin
  • Patent number: 11668844
    Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte, and identify patient administration factors that correlate with improper administration over a set of patients so as to identify administration risk factors to improve administration of radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: June 6, 2023
    Assignee: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
  • Patent number: 10852446
    Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: December 1, 2020
    Assignee: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
  • Patent number: 9939533
    Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: April 10, 2018
    Assignee: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
  • Publication number: 20160238716
    Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.
    Type: Application
    Filed: April 3, 2015
    Publication date: August 18, 2016
    Applicant: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
  • Publication number: 20150276937
    Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.
    Type: Application
    Filed: April 3, 2015
    Publication date: October 1, 2015
    Applicant: Lucerno Dynamics, LLC
    Inventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze