Patents Assigned to Lucerno Dynamics, LLC
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Patent number: 12061298Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte is presented. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system utilizes computer program code executable by a computer processor that performs the steps of receiving signal data, accessing reference data, and comparing the signal data to the reference data to determine a likelihood of improper administration of the radioactive analyte to the subject.Type: GrantFiled: May 2, 2023Date of Patent: August 13, 2024Assignee: Lucerno Dynamics, LLCInventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze, Steve Perrin
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Patent number: 11963808Abstract: Various embodiments of a device for in-vivo measurements radiopharmaceuticals used for diagnosis and monitoring of radiotherapy are presented. In some embodiments, the present disclosure relates to a device having a cannula that may include a measurement chamber, a radiation detector and a delivery lumen, wherein the device may be used to both deliver material to the patient (e.g., radiotracers used in radiopharmaceuticals) and measure levels and concentrations of radioactive material in, for example, the patient's blood both during and after administration of the radioactive material. In some embodiments, particles emitted by the radioactive material interact with a scintillation material, resulting in the release of light that may be transmitted, via the scintillation material and/or fiber optic material, to an optical detectors or processor for processing.Type: GrantFiled: May 21, 2021Date of Patent: April 23, 2024Assignee: Lucerno Dynamics, LLCInventors: Joshua G. Knowland, Ronald K. Lattanze, Paul Mozley, Steven Perrin
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Patent number: 11668844Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte, and identify patient administration factors that correlate with improper administration over a set of patients so as to identify administration risk factors to improve administration of radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.Type: GrantFiled: October 29, 2020Date of Patent: June 6, 2023Assignee: Lucerno Dynamics, LLCInventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
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Patent number: 10852446Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte. In some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.Type: GrantFiled: January 31, 2018Date of Patent: December 1, 2020Assignee: Lucerno Dynamics, LLCInventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
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Patent number: 9939533Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.Type: GrantFiled: April 3, 2015Date of Patent: April 10, 2018Assignee: Lucerno Dynamics, LLCInventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
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Publication number: 20160238716Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.Type: ApplicationFiled: April 3, 2015Publication date: August 18, 2016Applicant: Lucerno Dynamics, LLCInventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze
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Publication number: 20150276937Abstract: A system and method for the measurement of radiation emitted from an in-vivo administered radioactive analyte. Gamma radiation sensors may be used to determine the proper or improper administration of a radioactive analyte in some cases, the system employs a sensor having a scintillation material to convert gamma radiation to visible light, which enables embodiments of the sensor to be ex vivo. A light detector converts the visible light to an electrical signal. This signal is amplified and is processed to measure the captured radiation. Temperature of the sensor may be recorded along with this radiation measurement for temperature compensation of ex vivo embodiments. The sensor enables collection of sufficient data to support separate application to predictive models, background comparisons, or change analysis.Type: ApplicationFiled: April 3, 2015Publication date: October 1, 2015Applicant: Lucerno Dynamics, LLCInventors: Joshua G. Knowland, Charles W. Scarantino, Ronald K. Lattanze