Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
Type:
Application
Filed:
June 5, 2002
Publication date:
July 3, 2003
Applicant:
Ludwig Institute for Cancer Research and Helsinki University Licensing Ltd. OY
Inventors:
Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo