Abstract: The invention relates to the discovery of known molecule “ESCA/DPPA-2” and a so-called “cancer-testis antigen.” ESCA/DPPA-2 is also a possible cancer stem cell marker. One can determine presence of cancer by assaying for the molecule, and also prevent or treat cancer via administration of the molecule.
Type:
Application
Filed:
October 2, 2007
Publication date:
August 19, 2010
Applicant:
LUDWIG INSTITUTE FOR CONCER RESEARCH
Inventors:
Thomas John, Suzanne Svobodova, Jonathan Cebon, Otavia L. Caballero, Marilyn Monk