Patents Assigned to Luitpold Pharmaceuticals, Inc.
  • Methods and compositions for administration of iron
    Patent number: 10478450
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: November 19, 2019
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • Methods and compositions for administration of iron
    Patent number: 10434118
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: October 8, 2019
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • Methods and compositions for administration of iron
    Patent number: 10391117
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: August 27, 2019
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • Methods and compositions for administration of iron
    Patent number: 10314856
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: June 11, 2019
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • Methods and compositions for administration of iron
    Patent number: 8895612
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: November 25, 2014
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • METHODS FOR MODULATION OF PHOSPHORUS AND FGF23
    Publication number: 20140162974
    Abstract: Compositions and methods for decreasing phosphorus, decreasing cFGF23, or increasing iFGF23 in a subject. Such compositions and methods can be useful for treatment of conditions, disorders, or diseases associated with phosphorus or FGF23 disregulation.
    Type: Application
    Filed: March 5, 2013
    Publication date: June 12, 2014
    Applicant: LUITPOLD PHARMACEUTICALS, INC.
    Inventors: David B Bregman, Marc L Tokars
  • METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON
    Publication number: 20140099381
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Application
    Filed: December 9, 2013
    Publication date: April 10, 2014
    Applicant: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • Fatty amine drug conjugates
    Patent number: 8552054
    Abstract: The invention provides conjugates of fatty amines and pharmaceutical agents useful in treating cancer, viruses, psychiatric disorders. Compositions, pharmaceutical preparations, and methods of preparations of the fatty amine-pharmaceutical agent conjugates are provided.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: October 8, 2013
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Charles S. Swindell, Glenn J. Fegley
  • Device for intranasal administration
    Patent number: 8551454
    Abstract: Disclosed herein are vials and devices containing a ketorolac solution for intranasal administration and a head space comprising no more than about 10% v/v oxygen and which vials and devices are stored in an oxygen-impermeable pouch. Also disclosed are processes for preparing the vials and devices.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: October 8, 2013
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Roger Whiting, Ramachandran Thirucote
  • METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON
    Publication number: 20130230565
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Application
    Filed: March 19, 2013
    Publication date: September 5, 2013
    Applicant: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • DEVICE FOR INTRANASAL ADMINISTRATION OF KETOROLAC
    Publication number: 20130186391
    Abstract: Disclosed herein are vials and devices containing a ketorolac solution for intranasal administration and a head space comprising no more than about 10% v/v oxygen and which vials and devices are stored in an oxygen-impermeable pouch. Also disclosed are processes for preparing the vials and devices.
    Type: Application
    Filed: March 8, 2013
    Publication date: July 25, 2013
    Applicant: LUITPOLD PHARMACEUTICALS, INC.
    Inventor: LUITPOLD PHARMACEUTICALS, INC.
  • Methods and compositions for administration of iron
    Patent number: 8431549
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: April 30, 2013
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • Xanthones, thioxanthones and acridinones as DNA-PK inhibitors
    Patent number: 8404681
    Abstract: Compound that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods of inhibiting the DNA-PK biological activity, methods of sensitizing cells the agents that cause DNA lesions, and methods of potentiating cancer treatment are disclosed.
    Type: Grant
    Filed: March 19, 2004
    Date of Patent: March 26, 2013
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: James W. Halbrook, Edward A. Kesicki, Laurence E. Burgess, Stephen T. Schlachter, Charles T. Eary, Justin G. Schiro
  • Fatty acid-pharmaceutical agent conjugates
    Patent number: 8314077
    Abstract: The invention provides conjugates of fatty acids and pharmaceutical agents useful in treating noncentral nervous system conditions. Methods for selectively targeting pharmaceutical agents to desired tissues are provided.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: November 20, 2012
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Nigel L. Webb, Matthews O. Bradley, Charles S. Swindell, Victor E. Shashoua
  • Device for intranasal administration
    Patent number: 8277781
    Abstract: Disclosed herein are devices and processes for preparing a vial for an intranasal administration of a medicament where the vial comprises reduced oxygen content.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: October 2, 2012
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Roger Whiting, Ramachandran Thirucote
  • Materials and methods to potentiate cancer treatment
    Patent number: 8242115
    Abstract: Compounds that inhibit DNA-dependent protein kinase, compositions comprising the compounds, methods to inhibit the DNA-PK biological activity, methods to sensitize cells the agents that cause DNA lesions, and methods to potentiate cancer treatment are disclosed.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: August 14, 2012
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: James Halbrook, Edward A. Kesicki, Laurence E. Burgess, Stephen T. Schlachter, Charles T. Eary, Justin G. Schiro, Hongmei Huang, Michael Evans, Yongxin Han
  • GABA-LINKED ANTHRACYCLINE-LIPID CONJUGATES
    Publication number: 20120148595
    Abstract: The present invention relates to GABA-linked anthracycline-lipid conjugates and to methods of using the conjugates to treat cancer. Methods for making the GABA-linked anthracycline lipid conjugates are also provided.
    Type: Application
    Filed: March 11, 2010
    Publication date: June 14, 2012
    Applicant: Luitpold Pharmaceuticals, Inc.
    Inventors: Charles S. Swindell, Glenn G. Fegley, Hema M. Sundar, Richard Lawrence
  • METHODS AND COMPOSITIONS FOR ADMINISTRATION OF IRON
    Publication number: 20100266644
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Application
    Filed: May 25, 2010
    Publication date: October 21, 2010
    Applicant: LUITPOLD PHARMACEUTICALS, INC.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence
  • Fatty alcohol drug conjugates
    Patent number: 7816398
    Abstract: The invention provides conjugates of fatty alcohols and pharmaceutical agents useful in treating cancer, viruses, psychiatric disorders. Compositions, pharmaceutical preparations, and methods of preparation of the fatty alcohols-pharmaceutical agent conjugates are provided.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: October 19, 2010
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Charles S. Swindell, Glenn J. Fegley
  • Methods and compositions for administration of iron
    Patent number: 7754702
    Abstract: The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.
    Type: Grant
    Filed: January 8, 2007
    Date of Patent: July 13, 2010
    Assignee: Luitpold Pharmaceuticals, Inc.
    Inventors: Mary Jane Helenek, Marc L. Tokars, Richard P. Lawrence