Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
Type:
Grant
Filed:
August 21, 2020
Date of Patent:
March 22, 2022
Assignee:
LUMEN BIOSCIENCE, INC.
Inventors:
James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman
Abstract: Microorganisms with increased photosynthetic capacity are described. Increased photosynthetic capacity is achieved by down-regulating activity of the RpaB pathway. The microorganisms include Cyanobacteria, including genetically-modified Cyanobacteria.
Type:
Grant
Filed:
May 14, 2020
Date of Patent:
November 16, 2021
Assignee:
Lumen Bioscience, Inc.
Inventors:
James Roberts, Damian Carrieri, Mark Heinnickel
Abstract: Photosynthetic microorganisms with broadened light absorption capability and increased photosynthetic activity are described. Broadened light absorption is achieved by modifying the microorganism to utilize non-native bilins. Increased photosynthetic activity results from the broadened light absorption and can also result from a decrease in self-shading. The microorganisms include Cyanobacteria, including modified Cyanobacteria.
Type:
Grant
Filed:
July 7, 2016
Date of Patent:
September 29, 2020
Assignees:
LUMEN BIOSCIENCE, INC., RELIANCE HOLDING USA, INC.
Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
Type:
Grant
Filed:
February 14, 2020
Date of Patent:
September 1, 2020
Assignee:
LUMEN BIOSCIENCE, INC.
Inventors:
James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman
Abstract: Microorganisms with increased photosynthetic capacity are described. Increased photosynthetic capacity is achieved by down-regulating activity of the RpaB pathway. The microorganisms include Cyanobacteria, including genetically-modified Cyanobacteria.
Type:
Grant
Filed:
April 22, 2016
Date of Patent:
May 19, 2020
Assignees:
Lumen Bioscience, Inc., Reliance Holding USA, Inc.
Inventors:
James Roberts, Damian Carrieri, Mark Heinnickel
Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
Type:
Grant
Filed:
January 25, 2018
Date of Patent:
February 18, 2020
Assignee:
LUMEN BIOSCIENCE, INC.
Inventors:
James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman
Abstract: This disclosure describes techniques for creating stable, targeted mutations in Spirulina (Athrospiria) and Spirulina having stable, targeted mutations.
Abstract: This disclosure describes techniques for creating stable, targeted mutations in Spirulina (Athrospiria) and Spirulina having stable, targeted mutations.
Abstract: This disclosure describes techniques for creating stable, targeted mutations in Spirulina (Arthrospira) and Spirulina having stable, targeted mutations.
Abstract: This disclosure describes techniques for creating stable, targeted mutations in Spirulina (Athrospiria) and Spirulina having stable, targeted mutations.
Abstract: This disclosure describes modified photosynthetic microorganisms, including Cyanobacteria, that have a reduced amount of a light harvesting protein (LHP) and contain one or more introduced or overexpressed polynucleotides encoding one or more enzymes associated with lipid biosynthesis, and which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides.
Type:
Grant
Filed:
March 10, 2014
Date of Patent:
March 13, 2018
Assignee:
LUMEN BIOSCIENCE, INC.
Inventors:
James Roberts, Michael Carleton, Damian Carrieri, Jason W. Hickman