Abstract: A method and system for luminescence molecular imaging or tomography of a region of interest in a scattering medium is disclosed. The system comprises a non-linear luminescent marker material arranged in the scattering medium, one or more light sources positioned by at least one light source position for exciting said luminescent marker by excitation light emitted by said one or more light sources into an excitation volume, a detector at a luminescent light detection position detecting luminescence from said luminescent marker due to said excitation light, wherein said excitation light comprises pulsed excitation light.
Type:
Grant
Filed:
July 1, 2013
Date of Patent:
December 4, 2018
Assignee:
Lumito AB
Inventors:
Stefan Andersson Engels, Can Xu, Haichun Liu, Pontus Svenmarker
Abstract: A method and system for luminescence molecular imaging or tomography of a region of interest in a scattering medium is disclosed. The system comprises a non-linear luminescent marker material arranged in the scattering medium. Contrast and resolution of the imaging or tomography is thus improved. The non-linear marker is for instance configured to upconvert incoming light of an illumination wavelength. The non-linear power dependence of the marker enables further improvement of the imaging by using images taken with two or more excitation beams simultaneously.
Type:
Grant
Filed:
May 5, 2010
Date of Patent:
April 21, 2015
Assignee:
Lumito AB
Inventors:
Stefan Andersson-Engels, Can Xu, Haichun Liu, Johan Axelsson, Niclas Svensson, Pontus Svenmarker
Abstract: A method and system for luminescence molecular imaging or tomography of a region of interest in a scattering medium is disclosed. The system comprises a non-linear luminescent marker material arranged in the scattering medium. Contrast and resolution of the imaging or tomography is thus improved. The non-linear marker is for instance configured to upconvert incoming light of an illumination wavelength. The non-linear power dependence of the marker enables further improvement of the imaging by using images taken with two or more excitation beams simultaneously.
Type:
Application
Filed:
May 5, 2010
Publication date:
May 3, 2012
Applicant:
Lumito AB
Inventors:
Stefan Andersson-Engels, Can Xu, Haichun Liu, Johan Axelssen, Niclas Svensson, Pontus Svenmarker