Patents Assigned to Lumos Pharma, Inc.
  • Compactable oral formulations of ibutamoren
    Patent number: 11969416
    Abstract: The present disclosure relates to pharmaceutical solid forms and pharmaceutical compositions comprising ibutamoren or a pharmaceutically acceptable salt thereof, and methods for administering to a pediatric subject for treating growth hormone deficiency.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: April 30, 2024
    Assignee: Lumos Pharma, Inc.
    Inventors: Alpa B. Parikh, John C. McKew
  • Salts and prodrugs of 1-methyl-d-tryptophan
    Patent number: 11485705
    Abstract: Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: November 1, 2022
    Assignee: LUMOS PHARMA, INC.
    Inventors: Mario Mautino, Sanjeev Kumar, Firoz Jaipuri, Jesse Waldo, Hima Potturi, Hong Zhuang
  • Detecting and treating growth hormone deficiency
    Patent number: 11234969
    Abstract: Described herein is a new oral method for using MK-0677 for detecting growth hormone (GH) deficiency (GHD). Also described is a method of treating growth hormone (GH) deficiency (GHD) in children with a functional hypothalamic-pituitary GH axis.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: February 1, 2022
    Assignee: Lumos Pharma, Inc.
    Inventor: Michael Oliver Thorner
  • Detecting and treating growth hormone deficiency
    Patent number: 10898472
    Abstract: Described herein is a new oral method for using MK-0677 for detecting growth hormone (GH) deficiency (GHD). Also described is a method of treating growth hormone (GH) deficiency (GHD) in children with a functional hypothalamic-pituitary GH axis.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: January 26, 2021
    Assignee: Lumos Pharma, Inc.
    Inventor: Michael Oliver Thorner
  • Synthesis of cyclocreatine and analogs thereof
    Patent number: 10493062
    Abstract: Provided herein is a process for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof, using cynamide in the reaction.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: December 3, 2019
    Assignee: Lumos Pharma, Inc.
    Inventors: William R. Cantrell, Jr., William E. Bauta
  • Synthesis of cyclocreatine and analogs thereof
    Patent number: 10377721
    Abstract: Provided herein is a process and intermediates for the preparation of a compound of formula (I): or a pharmaceutically acceptable salt thereof, using cyanamide in the reaction.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: August 13, 2019
    Assignee: Lumos Pharma, Inc.
    Inventors: William R. Cantrell, Jr., William E. Bauta
  • Detecting and treating growth hormone deficiency
    Patent number: 10105352
    Abstract: Described herein is a new oral method for using MK-0677 for detecting growth hormone (GH) deficiency (GHD). Also described is a method of treating growth hormone (GH) deficiency (GHD) in children with a functional hypothalamic-pituitary GH axis.
    Type: Grant
    Filed: September 18, 2017
    Date of Patent: October 23, 2018
    Assignee: LUMOS PHARMA, INC.
    Inventor: Michael Oliver Thorner
  • Synthesis of cyclocreatine and analogs thereof
    Patent number: 10081605
    Abstract: Provided herein is a process and intermediates for the preparation of a compound of formula (I): or a pharmaceutically acceptable salt thereof, using cyanamide in the reaction.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: September 25, 2018
    Assignee: Lumos Pharma, Inc.
    Inventors: William R. Cantrell, Jr., William E. Bauta
  • SYNTHESIS OF CYCLOCREATINE AND ANALOGS THEREOF
    Publication number: 20170273950
    Abstract: Provided herein is a process for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof, using cynamide in the reaction.
    Type: Application
    Filed: September 1, 2015
    Publication date: September 28, 2017
    Applicant: Lumos Pharma, Inc.
    Inventors: William R. Cantrell, JR., William E. Bauta