Abstract: A method and structure for terminating an optical fiber are disclosed that provide an optical fiber termination structure with a small volume and very low return loss, even when the termination is in close proximity to reflective surfaces. In one example embodiment, the optical fiber termination reduces reflections into the one or more cores to a return loss of ?70 dB or less regardless of the presence of surfaces proximate the optical fiber termination. At the same time, a length of the optical fiber termination is less than 5 mm and a largest transverse dimension of the optical fiber termination is less than 325 um. The optical fiber termination is useful in fiber sensing applications in general and is particularly effective for terminating a multi-core fiber used in a distributed shape sensing application.

Abstract: A pegylated and hydroxlated trimetallic nitride endohedral metallofullerene is provided comprising a plurality of hydroxyl groups and one or more polyethylene glycol (PEG) moieties covalently bonded to a fullerene encapsulating a trimetallic nitride. Methods of pegylation and hydroxylation of trimetallic nitride endohedral metallofullerene and methods of using pegylated and hydroxlated trimetallic nitride endohedral metallofullerene are described.

Abstract: An interferometric measurement system measures a parameter using at least one optical waveguide. A memory stores reference interferometric pattern data associated with a segment of the optical waveguide. Interferometric detection circuitry detects and stores measurement interferometric pattern data associated with the segment of the optical waveguide during a measurement operation. A spectral range of the reference interferometric pattern of the optical waveguide is greater than a spectral range of the measurement interferometric pattern of the optical waveguide. A processor shifts one or both of the measurement interferometric pattern data and the reference interferometric pattern data relative to the other to obtain a match and to use the match to measure the parameter. An example parameter is strain.

Abstract: A passive sensor that is located on or adjacent to a structure that can be used to monitor the affect of environment on a structure or coating that is used to protect the structure. The sensor includes a parasitic element that interacts with the environment and influences the intensity of the electromagnetic response between the inductive element of the sensor and the antenna of the interrogation reader device. The condition of the parasitic element is determined by the radio frequency interaction of the reader antenna and the inductive element of the sensor. The parasitic element condition correlates to the environmental severity, or corrosivity of the environment and damage to metallic structures or protective coatings. An integrated circuit within the sensor is capable of storing identification, time, material, and measurement information. The sensor and system of the present invention is useful for tracking and monitoring cumulate environmental damage to a structure.

Abstract: An interferometric measurement system suppresses cross talk between optical waveguides used to measure one or more parameters. A first interferometric measurement channel coupled to a first waveguide, and a second interferometric measurement channel coupled to a second waveguide. At least one of the channels includes a reference light path in addition to the first and second waveguides. A reference path optical delay is associated with the reference light path, a first optical delay is associated with the input portion of at least one of the first and second interferometric measurement channels, and a second optical delay is associated with an output portion of the one interferometric measurement channel. A value of the first optical delay and a value the second optical delay are chosen to suppress crosstalk associated with the other of the first and second interferometric measurement channels in the one interferometric measurement channel over a predetermined length of the first waveguide.

Abstract: A method and apparatus for low voltage conversion and energy storage uses a charge pump array including a first set of capacitors in parallel with a second set of capacitors and switches for selectively coupling the first and second set of capacitors to a variable input DC voltage. A data processor programmably controls one or more of the switches to couple the first and second set of capacitors to the variable input DC voltage for a variable first time period during which the input DC voltage charges the first and second set of capacitors to a DC voltage level. An energy storage device is switchably coupled to an output of the charge pump array.

Abstract: Described herein are methods for treating inflammatory disorders or for inhibiting the build-up of arterial plaque. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.

Abstract: One or more mechanical parameters of a structure subjected to a force or condition are measured using distributed, optical fiber sensing technology. At least a curved portion an optical fiber having is attached to an object. A distributed, optically-based, strain sensing technique is used to determine strain information associated with multiple points along the curved portion of the fiber. The determined strain information is processed to generate one or more representations of one or more of the following: an expansion of the object, a thermal gradient associated with the object, or a stress-induced strain at multiple locations on the object corresponding to ones of the multiple points. An output is generated corresponding to the representation.

Abstract: Fullerene compounds represented by the formulae Cm[C(R)CON3]n, Cm[C(R)NCO]n, Cm[C(R)NHCORd]n, and Cm[C(R)NH2]n, wherein Cm represents a fullerene moiety having m carbon atoms, m represents an even integer from about 60 to about 200, n represents an integer of about 1 or more, R represents an electron-withdrawing group, and Rd represents an alkoxy or alkylamino group. In addition, processes for preparing these fullerene compounds involving reacting an acyl azide with a fullerene in the presence of a base.

Abstract: Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM?1 S?1 to about 300 mM?1 S?1 and forms a dispersion in water with entities having an average hydrodynamic radius of less than about 20 nm.

Abstract: An accurate measurement method and apparatus are disclosed for shape sensing with a multi-core fiber. A change in optical length is detected in ones of the cores in the multi-core fiber up to a point on the multi-core fiber. A location and/or a pointing direction are/is determined at the point on the multi-core fiber based on the detected changes in optical length. The accuracy of the determination is better than 0.5% of the optical length of the multi-core fiber up to the point on the multi-core fiber. In a preferred example embodiment, the determining includes determining a shape of at least a portion of the multi-core fiber based on the detected changes in optical length.

Abstract: A material characteristic measurement approach measures an internal state of a material by measuring the nonlinear shift in velocity induced by different acoustic energies. The technology for implementing this measurement approach is relatively simple, robust, permits portable measurements, does not require that an unloaded initial condition of the material be measured or otherwise known in order to determine a characteristic of the material, can be applied using one or more transducers, and does not require physical contact with the material.

Abstract: A functionalized trimetallic nitride endohedral fullerene based material can be represented according to the formula: A3-nXnN@Cm (R)o, wherein: where A and X are one or a combination of the following metal atoms: Sc, Y, La, Ce, Pr, Nd, Gd, Tb, Dy, Ho, Er, Tm, Lu; (n=0-3); N is nitrogen; Cm is a fullerene and m=about 60-about 200; and R is an organic, inorganic, or organometallic species. Related compositions, devices and methods are also described.

Abstract: A process for producing a fullerene derivative. The process comprises reacting a fullerene compound with a primary amine in the presence of a peroxide.

Abstract: An ultrasonic pulse echo apparatus detects an object that is moving with respect to stationary objects. An ultrasonic transducer transmits a series of ultrasound pulses in a direction that intersects a path of the moving object. An ultrasound receiver receives a series of lines of echoes from objects in the field of view of the ultrasonic signal. Each echo line corresponds to one of the ultrasonic pulses. A signal processor processes the echo lines from the moving object. The echo lines are time shifted by different amounts and combined at different time shifts to produce different composite lines. The composite line having an optimal signal-to-noise ratio is selected. Other signal processing enhancements are performed.

Abstract: Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified fullerene.

Abstract: Disclosed herein are methods of treating pruritus in a subject in need thereof. A method of treating pruritus comprises administering a therapeutically effective amount of fullerenes to a subject in need thereof.

Abstract: Described herein are methods for treating lack of hair growth or a reduction or loss of existing hair by stimulating and/or restoring hair growth, or preventing hair loss. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a fullerene.

Abstract: An ultrasonic pulse echo apparatus detects an object that is moving with respect to stationary objects. An ultrasonic transducer transmits a series of ultrasound pulses in a direction that intersects a path of the moving object. An ultrasound receiver receives a series of lines of echoes from objects in the field of view of the ultrasonic signal. Each echo line corresponds to one of the ultrasonic pulses. A signal processor processes the echo lines from the moving object. The echo lines are time shifted by different amounts and combined at different time shifts to produce different composite lines. The composite line having an optimal signal-to-noise ratio is selected. Other signal processing enhancements are performed.

Abstract: The present invention is directed toward a fiber optic position and shape sensing device and the method of use. The device comprises an optical fiber means. The optical fiber means comprises either at least two single core optical fibers or a multicore optical fiber having at least two fiber cores. In either case, the fiber cores are spaced apart such that mode coupling between the fiber cores is minimized. An array of fiber Bragg gratings are disposed within each fiber core and a frequency domain reflectometer is positioned in an operable relationship to the optical fiber means. In use, the device is affixed to an object. Strain on the optical fiber is measured and the strain measurements correlated to local bend measurements. Local bend measurements are integrated to determine position and/or shape of the object.