Patents Assigned to LUXEMBOURG BIO TECHNOLOGIES LTD.
  • Proton acceptor iminium/carbocation-type coupling agents
    Patent number: 8524898
    Abstract: Novel iminium-type coupling agents containing proton acceptors in their iminium moiety, which can be used beneficially as coupling agents in various chemical polypeptide and/or polynucleotide syntheses, and are particularly useful as yield enhancing and racemization suppressing coupling agents for use in peptide syntheses, are disclosed. Further disclosed are a process of preparing such iminium-type coupling agents and their use in the preparation of polypeptides and/or polynucleotides.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: September 3, 2013
    Assignee: Luxembourg Bio Technologies Ltd.
    Inventors: Fernando Albericio, Ayman El-Faham, Yoav Luxembourg, Ariel Ewenson
  • PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS
    Publication number: 20100144588
    Abstract: Novel iminium-type coupling agents containing proton acceptors in their iminium moiety, which can be used beneficially as coupling agents in various chemical polypeptide and/or polynucleotide syntheses, and are particularly useful as yield enhancing and racemization suppressing coupling agents for use in peptide syntheses, are disclosed. Further disclosed are a process of preparing such iminium-type coupling agents and their use in the preparation of polypeptides and/or polynucleotides.
    Type: Application
    Filed: May 15, 2008
    Publication date: June 10, 2010
    Applicant: LUXEMBOURG BIO TECHNOLOGIES LTD.
    Inventors: Fernando Albericio, Ayman El-Faham, Yoav Luxembourg, Ariel Ewenson