Patents Assigned to M.T.3, Inc.
  • METHOD FOR TREATING CANCER
    Publication number: 20240131044
    Abstract: There is provided with a method for treating cancer, comprising administering a pharmaceutical composition to a patient with cancer in combination with an anti-cancer agent, the pharmaceutical composition. A compound is represented by General Formula (I) or a pharmaceutically acceptable salt thereof: where R1 is an acyl residue from a fatty acid.
    Type: Application
    Filed: October 10, 2023
    Publication date: April 25, 2024
    Applicants: M.T.3, Inc., Colorado State University Research Foundation
    Inventors: Takamitsu Kato, Junko Maeda, Tomohiro Haga, Takaomi Fukuhara
  • Porphyrin compound or salt thereof, cancer therapeutic agent, photosensitizer, and fluorescent probe
    Patent number: 11643430
    Abstract: There is provided with a porphyrin compound represented by Formula (I) or a salt thereof; where A is a linking group represented as —X—NHCO— where X is a C1 to C6 alkylene group, each of R1, R2, R4, R5, R7, R8, R10, and R11 is a hydrogen atom, each of R3, R6, and R9 is a substituent of Formula; R12 is selected from a group of substituents represented by Formulae, R13 is a sulfo group, Ra, Rb, and Rc are substituents independently selected from C1 to C6 alkyl groups, and Rd is a hydrogen atom or a C1 to C6 alkyl group, and Rx is a substituent represented by General Formula. The porphyrin compound is useful as a cancer therapeutic agent, photosensitizer and fluorescent probe.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: May 9, 2023
    Assignees: M.T.3, INC., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hiroaki Horiuchi, Masahiko Oshige, Ichiro Matsuo, Tetsuo Okutsu, Shinji Katsura, Toshitada Yoshihara, Seiji Tobita, Fumio Sugawara, Kengo Sakaguchi
  • COMPOUND OR SALT THEREOF
    Publication number: 20220098227
    Abstract: There is provided with a compound. The compound is represented by formula or a salt thereof. R1 is an aliphatic hydrocarbon group having 10 to 26 carbon atoms.
    Type: Application
    Filed: September 2, 2021
    Publication date: March 31, 2022
    Applicants: M.T.3, Inc., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Masahiko OSHIGE, Ichiro MATSUO, Hiroaki HORIUCHI, Shinji KATSURA, Fumio SUGAWARA, Kengo SAKAGUCHI
  • Compound or salt thereof
    Patent number: 11267840
    Abstract: There is provided with a compound. The compound is represented by formula or a salt thereof. R1 is an aliphatic hydrocarbon group having 10 to 26 carbon atoms.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: March 8, 2022
    Assignees: M.T.3, INC., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Masahiko Oshige, Ichiro Matsuo, Hiroaki Horiuchi, Shinji Katsura, Fumio Sugawara, Kengo Sakaguchi
  • COMPOUND OR SALT THEREOF, AND METHOD
    Publication number: 20220064203
    Abstract: There is provided with a compound represented by Formula or a salt thereof; where A is a linking group represented as —X—NHCO— where X is a C1 to C6 alkylene group, each of R1, R2, R4, R5, R7, R8, R10, and R11 is a hydrogen atom, each of R3, R6, and R9 is a substituent of Formula; R12 is selected from a group of substituents represented by Formulae, R13 is a sulfo group, Ra, Rb, and Rc are substituents independently selected from C1 to C6 alkyl groups, and Rd is a hydrogen atom or a C1 to C6 alkyl group, and Rx is a substituent represented by General Formula.
    Type: Application
    Filed: August 31, 2021
    Publication date: March 3, 2022
    Applicants: M.T.3, Inc., NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY
    Inventors: Hiroaki HORIUCHI, Masahiko OSHIGE, Ichiro MATSUO, Tetsuo OKUTSU, Shinji KATSURA, Toshitada YOSHIHARA, Seiji TOBITA, Fumio SUGAWARA, Kengo SAKAGUCHI
  • METHOD OF TREATING CANCER
    Publication number: 20210393660
    Abstract: There is provided with a method of treating cancer. A set of administration of a compound represented by General Formula (I) or a pharmaceutically acceptable salt thereof to a patient, at a dose such that 8 mg/kg or less of the compound represented by General Formula (I) is administered, and irradiation to the patient immediately following the administration is repeated. A total dosage of the irradiation to a cancer is 10 Gy or more.
    Type: Application
    Filed: September 3, 2021
    Publication date: December 23, 2021
    Applicants: M.T.3, Inc., NIHON UNIVERSITY, SCHOOL CORPORATION, AZABU VETERINARY MEDICINE EDUCATIONAL INSTITUTION
    Inventors: Hiroeki SAHARA, Tomohiro NAKAYAMA, Takuya MARUO