Abstract: This disclosure includes, and results in the creation of, a printed carbon nanotube and/or graphene hybrid antenna and/or EMI shield, comprised of a conductive layer that comprises a metal mesh (MM) layer or a nanowire layer on a substrate, with a printed Signal Enhancement Layer (SEL) on the conductive layer. The SEL includes an ink that includes one or both of carbon nanotube (CNT) and graphene. The circuit pattern results after the “exposed” conductive layer (i.e., the regions where the CNT/graphene ink is not printed) is removed via chemical etching or mechanical cutting. The structure (the antenna/EMI shield) is preferably but not necessarily transparent.

Abstract: A process for reducing the environmental contaminants in a ISO 8217:2017 Table 2 compliant Feedstock Heavy Marine Fuel Oil and resulting product, the process involving: mixing a Feedstock Heavy Marine Fuel Oil with a Activating Gas to give a feedstock mixture; contacting the feedstock mixture with one or more catalysts to form a Process Mixture; separating the Product Heavy Marine Fuel Oil from the Process Mixture and, discharging the Product Heavy Marine Fuel Oil. The Product Heavy Marine Fuel Oil complies with ISO 8217:2017 Table 2 for residual marine fuel and the Environmental Contaminants, which are selected from the group consisting of: a sulfur; vanadium, nickel, iron, aluminum and silicon and combinations thereof, are less than 0.5 wt. %. The Product Heavy Marine Fuel Oil can be used as blending stock for an ISO 8217:2017 Table 2 compliant, IMO 2020 compliant, low sulfur heavy marine fuel composition.

Abstract: Described herein are compounds represented by formulas (IA) or (IB) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables R1, R3, R4, Y1, Y2, Ar, Z and n are as defined herein.

Abstract: A handling device (1) for tubular or elongate bowl-shaped workpieces such as pipette tips (4) or cups, said workpieces preferably being transported or being able to be transported on a workpiece carrier (T) during the production of said workpieces until packaging, the workpiece carrier (T) having receiving places (5) for the workpieces, which receiving places are arranged in a grid relative to each other, preferably with the stipulation that faulty workpieces located on the workpiece carrier (T) can be detected, and preferably with the stipulation that a removal station (25) is provided, by means of which the faulty workpieces can be removed from the receiving places (5) of a workpiece carrier (T), receiving places (5) thus being freed up, freed-up receiving places (5) of the workpiece carrier (T) being able to be loaded with faultless workpieces by means of the handling device, the handling device comprising a refill magazine (2), which has magazine places (3) arranged next to each other, each magazine place

Abstract: A bundle of carbon nanotubes (CNT), comprising a plurality of CNT with lengths of at least about 7 microns, wherein the bundle has a diameter of less than about 12 nm.

Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.

Abstract: A device that regulates, monitors, and provides data on the progress of a large-volume injector during its injection sequence. The device comprises an injector and a monitor assembly. The injector has a syringe having a plunger, and a biasing device that biases the plunger through the syringe. The monitor assembly comprises a resistance unit configured to resist movement of the plunger, a gear connected to the plunger by the resistance unit, and a control unit configured to monitor the position, and regulate the rotation, of the gear. Wherein linear movement of the plunger causes the gear to rotate so that the control unit generates information on the position of the plunger.

Abstract: An isolated protein comprising a mutant soluble activin II receptor (ActRIIA or ActRIIB) extracellular domain (Ac-tRIIA-ECD or ActRIIB-ECD), wherein said mutant soluble ActRIIA-ECD or ActRIIB-ECD comprises a mutation to remove the N-linked glycosylation site corresponding to position N18 of SEQ ID NO: 1.

Abstract: The present invention relates to a swimming pool structure having at least one edge zone and a water collection, filtering and recirculation circuit, the latter including at least one well zone (WZ) for falling water, at least one filter mounted in the well zone and designed to intercept the water falling into it.

Abstract: The present invention provides a DNA-targeting RNA comprising a single-guide RNA (sgRNA) and a ribonucleotide sequence rich in adenine ribonucleotide, and its use in gene editing, and a method for improving the efficiency of sgRNA-mediated gene editing, comprising a step of adding a ribonucleotide sequence rich in adenine ribonucleotide at 3? end of the sgRNA.

Abstract: Provided herein are compositions and methods for facilitating or enhancing delivery of nucleic acids, such as synthetic mRNAs, into cells or tissues. Such compositions and methods may include use of a targeting moiety-conjugated, such as an N-acetylgalactosamine (GalNAc)-conjugated, oligonucleotide to facilitate or enhance delivery.

Abstract: Described herein are compounds represented by formulas (IA) or (IB) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the same and methods of preparing and using the same. The variables R1, R3, R4, Y1, Y2, Ar, Z and n are as defined herein.

Abstract: A bicycle handlebar, for a bicycle, is arranged for providing at least one function for the purpose of at least one subsystem of the bicycle. The bicycle handlebar includes a head tube part that during use, at least partly, substantially extends along the head tube, a left handlebar bend with a handle end that extends to the left side from the head tube part, and a left handlebar bend with a handle end that extends to the right side from the head tube part. The bicycle handlebar includes at least an internal feedthrough channel from at least one of the left handlebar bend and right handlebar bend and wherein the at least one internal feedthrough channel extends into the head tube part.

Abstract: Provided are novel dipeptide repeat (DPR) specific antibodies (e.g., human-derived antibodies) as well as synthetic variants and biotechnological derivatives thereof, capable of binding C9orf72 poly-glycine-alanine DPRs, as well as methods and uses related thereto. The antibody of the present invention can be used in pharmaceutical and diagnostic compositions for DPR protein-targeted immunotherapy and diagnostics.

Abstract: Crop input application systems, methods and apparatus are provided. In some embodiments, an irrigation system is provided with a reel in fluid communication with a wellhead, secondary cart or fluid supply line outlet. In some embodiments, a drop assembly is incorporated in an irrigation system. In some embodiments, a crop applicator system traverses a field portion at a first speed in a first direction and then traverses the field portion at a second, lower speed in a second, opposite direction.

Abstract: Provided are compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R7, R8, R9, A1, A2, Q1, Q2, Q3, A, Z, m and n are as defined herein; pharmaceutical compositions comprising said compounds or pharmaceutically acceptable salts thereof, and pharmaceutically acceptable excipients; and methods of treating a disorder responsive to inhibition of Bruton's tyrosine kinase using said compounds, or pharmaceutically acceptable salts thereof, or said pharmaceutical compositions.

Abstract: The invention relates to methods of assessing a patient's risk of developing Progressive multifocal leukoencephalopathy (PML).

Abstract: An aluminum brazing sheet has a multilayer structure of two or more layers of at least a core material and a brazing material, wherein an Al—Si—Mg—Bi-based brazing material containing, by mass %, 0.01% to 2.0% of Mg, 1.5% to 14.0% of Si, and 0.005% to 1.5% of Bi is clad on one surface or both surfaces of the core material to be located at an outermost surface of the aluminum brazing sheet, in the Al—Si—Mg—Bi based brazing material, there are more than 10 Mg—Bi-based compounds having a diameter of 0.01 ?m or more and less than 5.0 ?m when observed in a surface layer plane direction and there are less than 2 Mg—Bi-based compounds having a diameter of 5.0 ?m or more, and in the brazing material, there are less than 5 Bi particles having a diameter of 5.0 ?m or more when observed in the surface layer plane direction.

Abstract: Disclosed herein are antisense compounds and methods for decreasing Tau mRNA and protein expression. Such methods, compounds, and compositions are useful to treat, prevent, or ameliorate Tau-associated diseases, disorders, and conditions.

Abstract: Provided herein are systems for determining a stretch condition of a tissue and assessing the stiffness of the tissue. Also provided herein are methods for using the systems for measuring stiffness of a tissue, assessing the effect of an agent on a tissue, and identifying subjects having a disease or disorder associated with increased or decreased stiffness of a tissue.