Patents Assigned to MACEF
  • Patent number: 7291627
    Abstract: The invention concerns dihydroimidazo[5,1-a]-?-carboline compounds of general formula (I) wherein in particular, R1, R2, R3, R4, R6 and R7, identical or different, independently of one another, present a hydrogen, halogen atom, an alkyl, hydroxyl, alkoxy, trihalogenoalkyl, alkylamino, dialkylamino, aryl, arylalkyl, carboxy, alkylcarbonyloxy, acyl, aryloxy or arylalkoxy group; R5 represents a hydrogen atom, an alkyl or arylalkyl group; and their isomers as well as their addition salts to a pharmaceutically acceptable acid. The inventive compounds are for use in medicine, in particular as hypnotics.
    Type: Grant
    Filed: May 16, 2002
    Date of Patent: November 6, 2007
    Assignee: MACEF
    Inventors: Jean-Bernard Fourtillan, Marianne Fourtillan, Omar Karam, Fabien Zunino, Jean-Claude Jacquesy, Jean-Pierre Tafani
  • Patent number: 6335346
    Abstract: The invention relates to pyrrolo[3,4-b]quinoline derivatives of general formula (I) wherein X represents an oxygen atom or a sulphur atom. Said derivatives have a hypnotic or sedative effect.
    Type: Grant
    Filed: December 26, 2000
    Date of Patent: January 1, 2002
    Assignees: MACEF, Laboratoires Besins Iscovesco
    Inventors: Jean-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Omar Karam, Fabien Zunino, Marie-Paule Jouannetaud