Patents Assigned to Macherey, Nagel & Co.
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Patent number: 5428067Abstract: A column packing material to be used in gel permeation chromatography (GPC) consists of support particles with a mean particle diameter of 1 to 50.mu. of which the matrix is formed by an inorganic or organic, polymeric and porous hard material with a mean pore diameter of 6 to 50 nm and a pore volume of 0.1 to 3 ml/g, the matrix pores containing chemically bound polymer chains. The column packing material of the invention is characterized in that the polymer chains consist of linear, permeable and not-crosslinked polymers with an upper exclusion limit between 200 and 200,000, the pores of the matrix being entirely filled by the polymer chains. The method of the invention is characterized in that the pores of the support particles are filled by polymer chains chemically bound to the pore surfaces, these polymer chains being permeable to solvents and partly to dissolved substances.Type: GrantFiled: November 19, 1992Date of Patent: June 27, 1995Assignee: Macherey, Nagel & Co.Inventors: Gunter Wulff, Milan Minarik, Ralf J. Oerschkes
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Patent number: 5342515Abstract: This invention relates to a chromatographic column with a separation column which is equipped on at least one side with an end threading mechanism for connecting a capillary, a precolumn, or another separation column, whereby the end threading mechanism has a support nut surrounding the column tube and a coupling nut, and the support nut is supported towards the corresponding end of the separation column at a stop part which is held in a recess at the separation column wherein the column has several axially consecutive recesses.Type: GrantFiled: October 29, 1993Date of Patent: August 30, 1994Assignee: Macherey, Nagel & Co.Inventor: Edmund Radmacher
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Patent number: 5198429Abstract: Substituted cyclodextrins of the general formula ##STR1## in which R.sup.2 and R.sup.6 mean straight-chain or branched alkyl or alkenyl groups with 1 to 8 carbon atoms or cycloalkyl groups with 5 to 8 carbon atoms which can be the same or different, andR.sup.3 represents a straight-chain or branched alkyl or alkenyl group, which can be the same or different to the residues R.sup.2 and R.sup.6, with 1 to 8 carbon atoms or a cycloalkyl group with 5 to 8 carbon atoms, oran acyl group with an optionally substituted, saturated or olefinically unsaturated aliphatic or cycloaliphatic or with an aromatic hydrocarbon residue with 1 to 8 carbon atoms, andn=6 or 7,a process for their production, and a process for the separation of chiral organic compounds by chromatographic separation processes in which the substituted cyclodextrins are used as stationary phase.Type: GrantFiled: December 3, 1990Date of Patent: March 30, 1993Assignee: Macherey-Nagel & Co.Inventors: Wilfried Konig, Gerhard Wenz, Sabine Lutz, Eva von der Bey
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Patent number: 5164427Abstract: A column packing material to be used in gel permeation chromatography (GPC) consists of support particles with a mean particle diameter of 1 to 50 .mu. of which the matrix is formed by an inorganic or organic, polymeric and porous hard material with a mean pore diameter of 6 to 50 nm and a pore volume of 0.1 to 3 ml/g, the matrix pores containing chemically bound polymer chains. The column packing material of the invention is characterized in that the polymer chains consist of linear, permeable and not-crosslinked polymers with an upper exclusion limit between 200 and 200,000, the pores of the matrix being entirely filled by the polymer chains. The method of the invention is characterized in that the pores of the support particles are filled by polymer chains chemically bound to the pore surfaces, these polymer chains being permeable to solvents and partly to dissolved substances.Type: GrantFiled: December 13, 1991Date of Patent: November 17, 1992Assignee: Macherey, Nagel & Co.Inventors: Gunter Wulff, Milan Minarik, Ralf J. Oerschkes
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Patent number: 5091433Abstract: A column Packing material to be used in gel permeation chromatography (GPC) consists of support particles with a mean particle diameter of 1 to 50 .mu. of which the matrix is formed by an inorganic or organic, polymeric and porous hard material with a mean pore diameter of 6 to 50 nm and a pore volume of 0.1 to 3 ml/g, the matrix pores containing chemically bound polymer chains. The column packing material of the invention is characterized in that the polymer chains consist of linear, permeable and not-crosslinked polymers with an upper exclusion limit between 200 and 200,000, the pores of the matrix being entirely filled by the polymer chains. The method of the invention is characterized in that the pores of the support particles are filled by polymer chains chemically bound to the pore surfaces, these polymer chains being permeable to solvents and partly to dissolved substances.Type: GrantFiled: October 12, 1990Date of Patent: February 25, 1992Assignee: Macherey, Nagel & Co.Inventors: Gunter Wulff, Milan Minarik, Ralf J. Oerschkes
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Patent number: 4670402Abstract: The invention relates to the use of a compound of the chemical formula: ##STR1## in which: R.sub.1 and R.sub.2 are the same or different and represent hydrogen, halogen, and a lower alkyl or alkoxy group containing 1 to 4 carbon atoms, a (C.sub.1 -C.sub.4)-dialkylamino group, an acetylamino group, a nitro group or an aromatic group which may be substituted or anellated;n is an integer from 1 to 4, preferably 1 or 2;m is likewise an integer from 1 to 4, preferably 1 or 2; andR.sub.Type: GrantFiled: December 27, 1985Date of Patent: June 2, 1987Assignee: Macherey-Nagel & Co.-ChemikalienhandelInventor: Karl-Heinz Flegler
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Patent number: RE36092Abstract: Substituted cyclodextrins of the general formula ##STR1## in which R.sup.2 and R.sup.6 mean straight-chain or branched alkyl or alkenyl groups with 1 to 8 carbon atoms or cycloalkyl groups with 5 to 8 carbon atoms which can be the same or different, andR.sup.3 represents a straight-chain or branched alkyl or alkenyl group, which can be the same or different to the residues R.sup.2 and R.sup.6, with 1 to 8 carbon atoms or a cycloalkyl group with 5 to 8 carbon atoms, oran acyl group with an optionally substituted, saturated or olefinically unsaturated aliphatic or cycloaliphatic or with an aromatic hydrocarbon residue with 1 to 8 carbon atoms, andn=6 or 7,a process for their production, and a process for the separation of chiral organic compounds by chromatographic separation processes in which the substituted cyclodextri are used as stationary phase.Type: GrantFiled: September 5, 1995Date of Patent: February 9, 1999Assignee: Macherey-Nagel & Co.Inventors: Wilfried Konig, Gerhard Wenz, Sabine Lutz, Eva von der Bey