Abstract: Abstract of the Disclosure This invention relates to a cream of the kind described in the preamble of claim 1 for topical treatment of visibly photodamaged skin caused by processes involving the influence of free radicals and where the cream also affects the energy production of the cells, wherein the active ingredients of the cream is carried in stabilizing cream base. The cream is characterized in 0.5% and 7% by weight d,l-?-lipoic acid, between 0.05 and 0.5% by weight coenzyme Q-10, between 0.001 and 3% by weight acetyl-l-carnitine hydrochloride, which constitute the active ingredients, whereby having a compound synergy effect.