Patents Assigned to MacroPore, Inc.
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Patent number: 6531146Abstract: Resorbable polylactide polymer scar tissue reduction barrier membranes and methods of their application are disclosed. The scar-tissue reduction barrier membranes are constructed entirely of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The scar tissue reduction barrier membranes are formed to have thicknesses on the order of microns, such as, for example, thicknesses between 10 and 300 microns. The membranes are preshaped with welding flanges and stored in sterile packaging.Type: GrantFiled: March 12, 2001Date of Patent: March 11, 2003Assignee: MacroPore, Inc.Inventors: Christopher J. Calhoun, Ralph E. Holmes
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Patent number: 6391059Abstract: A resorbing, flexible implant in the form of a continuous macro-porous sheet (42) is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vitro repair. The membrane (42) has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature, and connective tissue cells derived from the adjacent soft tissues including the periosteum, can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature, and does not collapse.Type: GrantFiled: October 16, 2000Date of Patent: May 21, 2002Assignee: MacroPore, Inc.Inventors: Stefan M. Lemperle, Christopher J. Calhoun
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Patent number: 6343531Abstract: A high-torque fastener having a threaded shaft and a star-shaped head is disclosed. The high-torque fastener is made of a resorbable or other non-magnetic material. A mating driver snugly fits around the star-shaped head of the fastener, to thereby apply torque to the perimeter of the star-shaped head. The driver can be made disposable, and the driver and fastener packaged together in a single, disposable assembly. Additionally, the driver can be color coded to indicate the size of the fastener which is pre-attached to the driver in the packaging.Type: GrantFiled: June 25, 2001Date of Patent: February 5, 2002Assignee: MacroPore, Inc.Inventor: James Peter Amis
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Publication number: 20020001609Abstract: Resorbable polylactide polymer scar tissue reduction barrier membranes and methods of their application are disclosed. The scar-tissue reduction barrier membranes are constructed entirely of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The scar tissue reduction barrier membranes are formed to have thicknesses on the order of microns, such as, for example, thicknesses between 10 and 300 microns. The membranes are preshaped with welding flanges and stored in sterile packaging.Type: ApplicationFiled: March 12, 2001Publication date: January 3, 2002Applicant: MacroPore, Inc.Inventors: Christopher J. Calhoun, Ralph E. Holmes
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Patent number: 6280473Abstract: A resorbable, flexible implant in the form of a continuous macro-porous sheet is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vivo repair. The membrane has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature and connective tissue cells derived from the adjacent soft tissues including the periosteum can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature and does not collapse.Type: GrantFiled: February 23, 1999Date of Patent: August 28, 2001Assignee: MacroPore, Inc.Inventors: Stephan M. Lemperle, Christopher J. Calhoun
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Patent number: 6269716Abstract: A high-torque fastener having a threaded shaft and a star-shaped head is disclosed. The high-torque fastener is made of a resorbable or other non-magnetic material. A mating driver snugly fits around the star-shaped head of the fastener, to thereby apply torque to the perimeter of the star-shaped head. The driver can be made disposable, and the driver and fastener packaged together in a single, disposable, assembly. Additionally, the driver can be color coded to indicate the size of the fastener which is pre-attached to the driver in the packaging.Type: GrantFiled: May 22, 2000Date of Patent: August 7, 2001Assignee: MacroPore, Inc.Inventor: James Peter Amis
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Patent number: 5919234Abstract: A resorbable, flexible implant in the form of a continuous macro-porous sheet is disclosed. The implant is adapted to protect biological tissue defects, especially bone defects in the mammalian skeletal system, from the interposition of adjacent soft tissues during in vivo repair. The membrane has pores with diameters from 20 microns to 3000 microns. This porosity is such that vasculature and connective tissue cells derived from the adjacent soft tissues including the periosteum can proliferate through the membrane into the bone defect. The thickness of the sheet is such that the sheet has both sufficient flexibility to allow the sheet to be shaped to conform to the configuration of a skeletal region to be repaired, and sufficient tensile strength to allow the sheet to be so shaped without damage to the sheet. The sheet provides enough inherent mechanical strength to withstand pressure from adjacent musculature and does not collapse.Type: GrantFiled: August 19, 1996Date of Patent: July 6, 1999Assignee: MacroPore, Inc.Inventors: Stefan M. Lemperle, Christopher J. Calhoun