Abstract: A method for measuring hemoglobin concentration in a whole blood sample is disclosed. The method may include mixing a whole blood sample with a lysing agent, followed by manual agitation, flowing the whole blood or mixture into a reservoir of a sensor, the sensor comprising a transparent portion configured to allow an optical measurement of an absorbance or reflectance of the whole blood sample in the reservoir of the sensor; detecting, using an analyzer into which at least a portion of the sensor has been inserted, the whole blood sample in the reservoir of the sensor; upon detecting the liquid whole blood sample in the reservoir, optically measuring an absorbance or reflectance of the whole blood sample using a light source and a detector in the analyzer; and determining a concentration of hemoglobin in the whole blood sample based on the measured absorbance or reflectance and a calibration curve that relates the absorbance or reflectance to the concentration of hemoglobin in the whole blood sample.
Type:
Grant
Filed:
November 11, 2019
Date of Patent:
June 15, 2021
Assignee:
Magellan Diagnostics, Inc.
Inventors:
Norman F. Sheppard, Jr., Gary Conrad Jensen
Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
Type:
Grant
Filed:
September 11, 2017
Date of Patent:
November 12, 2019
Assignee:
Magellan Diagnostics, Inc.
Inventors:
Norman F. Sheppard, Jr., Gary Conrad Jensen
Abstract: A sensor and analyzer for measuring an analyte in a liquid sample are disclosed. The sensor includes a substrate with a reservoir disposed therein. The reservoir may include a top surface and a bottom surface, at least one transparent portion forming at least a part of the bottom surface of the reservoir, and a reflector disposed on the upper surface of the reservoir at a location opposite the at least one transparent portion. The analyzer may include a support surface, an aperture extending through the support surface, a light source disposed below the support surface and oriented so that at least a portion of the light emitted from the light source passes through the aperture, and a detector configured to measure an intensity of light received at the detector.
Type:
Grant
Filed:
December 22, 2015
Date of Patent:
September 12, 2017
Assignee:
Magellan Diagnostics, Inc.
Inventors:
Norman F. Sheppard, Jr., Gary Conrad Jensen
Abstract: A sensor having a bifurcated flow path and method for using the same is disclosed. In some embodiments, the sensor has two flow channels into which sample flow is induced by capillary action, wherein the flow channels are in contact with electrodes configured to generate an electrochemical reaction in the flow channels which can be measured and correlated to the level of an analyte in the sample. In some embodiments, the levels of more than one analyte can be measured using a single sensor.
Type:
Application
Filed:
March 14, 2013
Publication date:
September 18, 2014
Applicant:
MAGELLAN DIAGNOSTICS, INC.
Inventors:
Matthew K. Musho, Mohammad Hossein Maleknia
Abstract: An apparatus and method for analyzing multiple samples is disclosed. In some embodiments, the apparatus and method use a multi-channel analyzer configured to simultaneously process results from a plurality of sample ports. The multi-channel analyzer further comprises a system for storing and transmitting the sample results from the plurality of samples, including unique sample identifiers. In some embodiments, the sample results may be transmitted to a laboratory information management system, a hospital network, or other similar location.