Abstract: The present invention relates to esters of pantetheine and pantethine with 3-pyridineacetic or 3-(3-pyridylmethoxycarbonyl)-propionic acid and to therapeutically acceptable acid addition salts thereof. The compounds show a high degree of hypolipemic activity.
Type:
Grant
Filed:
July 10, 1984
Date of Patent:
February 18, 1986
Assignee:
Maggioni Farmaceutici S.p.A.
Inventors:
Giampaolo Picciola, Piergiorgio Gentili, Franco Ravenna, Mario Riva
Abstract: Dipeptides are claimed which consist of a mercaptoalkanoic acid and a derivative of said acid, namely an S-alkyl-, aralkyl-, aryl-, acyl- or aroyl derivative with methionine, a methionine ester or a methionine amide, as well as their salts with metallic cations and organic bases. These compounds have the property of protecting the liver against intoxications and have sedative and hypnotic properties.
Type:
Grant
Filed:
December 21, 1982
Date of Patent:
July 17, 1984
Assignee:
Maggioni Farmaceutici, S.p.A.
Inventors:
Giampaolo Picciola, Franco Ravenna, Mario Riva