Abstract: Novel bicyclic alkoxy- and alkylthio-substituted aminoalcohols of formula (I). The compounds show anti-hypertensive, platelet aggregation inhibiting, hypolipemic, antianoxic, spasmolytic, antithrombotic, calcium antagonizing and neuroleptic activity.
Type:
Grant
Filed:
June 4, 1987
Date of Patent:
February 20, 1990
Assignee:
Maggioni-Winthrop S.p.A.
Inventors:
Giampaolo Picciola, Mario Riva, Franco Ravenna, Piergiorgio Gentili
Abstract: The invention is concerned with fused cycloaliphatic aminoalcohols having pharmacological activity as anti-hypertensive, platelet aggregation inhibiting, hypolipemic, antianoxic and spasmolytic activity. The compounds have the generic formula ##STR1## in which the symbol n is an integer selected from 1 to 2, the compounds pertaining therefore to the indanol and tetralol series.
Type:
Grant
Filed:
December 10, 1986
Date of Patent:
May 2, 1989
Assignee:
Maggioni-Winthrop S.P.A.
Inventors:
Giampaolo Picciola, Mario Riva, Franco Ravenna, Piergiorgio Gentili
Abstract: The invention is concerned with dihydrobenzothiophene and thiochromane derivatives of the generic formula ##STR1## The compounds show anti-hypertensive, platelet aggregation inhibiting, hypolipemic, antianoxic spasmolytic, anthithrombotic, calcium antagonizing and neuroleptic activity.
Type:
Grant
Filed:
December 10, 1986
Date of Patent:
December 13, 1988
Assignee:
Maggioni-Winthrop S.p.A.
Inventors:
Giampaolo Picciola, Mario Riva, PierGiuseppe De Meglio, Piergiorgio Gentili