Abstract: Biodegradable microspheres having a diameter of 10-2000 ?m having cross-linked hydrolysed starch onto which at least one type of ligand has been coupled via a carboxylic ester bond. The ligand shall be an endogenous, charged molecule with a molecular mass of less than 1000 Da having at least one additional carboxylic acid function in addition to the one utilised for coupling the ligand to the microsphere and/or at least one amine function. On average 0.05-1.5 ligands are coupled to each glucose moiety in the hydrolysed starch.
Type:
Grant
Filed:
November 17, 2010
Date of Patent:
July 18, 2017
Assignee:
Magle AB
Inventors:
Malin Malmsjo, Eddie Thordarson, Sten Peter Apell, Peter Fyhr
Abstract: Biodegradable microspheres having a diameter of 10-2000 ?m having cross-linked hydrolysed starch onto which at least one type of ligand has been coupled via a carboxylic ester bond. The ligand shall be an endogenous, charged molecule with a molecular mass of less than 1000 Da having at least one additional carboxylic acid function in addition to the one utilised for coupling the ligand to the microsphere and/or at least one amine function. On average 0.05-1.5 ligands are coupled to each glucose moiety in the hydrolysed starch.
Type:
Application
Filed:
November 17, 2010
Publication date:
September 27, 2012
Applicant:
MAGLE AB
Inventors:
Malin Malmsjo, Eddie Thordarson, Sten Peter Apell, Peter Fyhr
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