Patents Assigned to Magyar Tudományos Akadémia Természettudományi Kutatóközpont
  • MDR-reversing 8-hydroxy-quinoline derivatives
    Patent number: 10744127
    Abstract: The present invention is related to 8-hydroxy-quinoline derivatives having multidrug-resistance reversing activity with improved selectivity and increased cytotoxicity towards multidrug-resistant cancer cells, preparation thereof and use of the same in the treatment of cancer, especially multidrug-resistant variants thereof.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: August 18, 2020
    Assignee: Magyar Tudományos Akadémia Természettudományi Kutatóközpont
    Inventors: Gergely Szakács, Tibor Soós, Roberta Ferenczi-Palkó, András Füredi, Szilárd Tóth, Dóra Türk, Veronika Pape, Ferenc Fülöp, István Szatmári, György Dormán
  • MDR-REVERSING 8-HYDROXY-QUINOLINE DERIVATIVES
    Publication number: 20190151306
    Abstract: The present invention is related to 8-hydroxy-quinoline derivatives having multidrug-resistance reversing activity with improved selectivity and increased cytotoxicity towards multidrug-resistant cancer cells, preparation thereof and use of the same in the treatment of cancer, especially multidrug-resistant variants thereof.
    Type: Application
    Filed: April 5, 2017
    Publication date: May 23, 2019
    Applicant: Magyar Tudományos Akadémia Természettudományi Kutatóközpont
    Inventors: Gergely SZAKÁCS, Tibor SOÓS, Roberta FERENCZI-PALKÓ, András FÜREDI, Szilárd TÓTH, Dóra TÜRK, Veronika PAPE, Ferenc FÜLÖP, István SZATMÁRI, György DORMÁN