Abstract: Described are anatomically specified conformation computed tomography (ASC-CT) systems, which are fully tomographic x-ray imaging systems configured to conform to the contour of the anatomy of interest and perform a near scatter-free image acquisition, thereby providing an enhanced contrast resolution in the reconstructed CT image volume. The apparatus comprises independently controlled, yet synchronized, x-ray generation and detection assemblies configured to perform a tomographic image acquisition. The method of image acquisition entails adjusting the layout of the x-ray panels within the detector assembly based on the shape of the anatomy, followed by capturing a collimated, narrow x-ray beam composed of primary photons while sweeping a circular trajectory around the anatomy placed in the field of view, resulting in a conforming sinogram of the anatomy.

Abstract: Described are apparatus and methods of operation for three dimensional fluence modulation and scatter shielding for dedicated computed tomography (CT). Through the disclosed invention, the number of incident photons on the field of view (FOV) of the imaging system becomes proportional to the path length of the photon through the anatomy of interest. The apparatus is comprises a patient specific x-ray fluence modulation unit and a scatter shield unit. The fluence modulation unit reduces radiation dose differences across the anatomical part and the dynamic range requirements for the x-ray detector. The scatter shield unit is intended for preventing the scattered beams from reaching the x-ray detector. The internal structures of each unit are composed of elements with adjustable positions dependent on the specific shape of the object in the field-of-view (FOV). Method of operation are also provided.