Patents Assigned to Mallinckrodt Diagnostica (Germany) GmbH - Justia Patents Search

Patents Assigned to Mallinckrodt Diagnostica (Germany) GmbH

Procedure for the irreversible binding of proteins onto polystyrene surfaces with retention of their biological activity, polystyrene surfaces obtained by this procedure, and their use

Patent number: 4654299

Abstract: A procedure for the immobilization of proteins on polystyrene surfaces which includes a pre-treatment of the polystyrene surface with a bis-diazonium compound of the general formula I where ##STR1## R1 stands for a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group or a nitro group and whereR2 stands for a hydrogen atom, a halogen atom or an alkyl group and where X stands for an anion and the subsequent adsorption of the protein on the surface pretreated.Proteins immobilized by its procedure may be used in immunoassays.

Type: Grant

Filed: March 21, 1984

Date of Patent: March 31, 1987

Assignee: Mallinckrodt Diagnostica (Germany) GmbH

Inventor: Dierck Lentfer