Patents Assigned to Mandom Corporation
  • Publication number: 20230057230
    Abstract: The present invention provides a novel method for detecting an indicator of T cell lymphoma. The method for detecting an indicator of T cell lymphoma includes the step of detecting acetylated tubulin in a T cell that has been collected from a subject.
    Type: Application
    Filed: January 7, 2021
    Publication date: February 23, 2023
    Applicants: MANDOM CORPORATION, OSAKA UNIVERSITY, PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY
    Inventors: Manami Toriyama, Fumitaka Fujita, Fumihiro Okada, Akimichi Morita, Motoki Nakamura
  • Patent number: 11464720
    Abstract: This TRPA1 activity inhibitor contains a compound represented by formula (I) wherein R1, R2, R3 and R4 each independently represent a hydrogen atom or a methyl group, and R5, R6, R7 and R8 each independently represent a hydrogen atom, a methyl group or —O—R9—OH (in the formula, R9 represents an alkylene group optionally having a substituent group), provided that at least one group of R5, R6, R7 and R8 is —O—R9—OH.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: October 11, 2022
    Assignees: MANDOM CORPORATION, TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Masayuki Takaishi, Fumitaka Fujita, Hironori Shimizu, Shu Sakuyama, Kenya Ishida, Kenji Maruyama
  • Publication number: 20210361549
    Abstract: Provided is an antiperspirant which serves to control secretion of sweat secreted from sweat glands and is capable of doing so by acting on sweat glands without closing sweat pores, the antiperspirant containing, as an active ingredient to control secretion of sweat secreted from sweat glands, at least one type of pentacyclic compound selected from the group consisting of compounds represented by formula (I): and derivatives thereof, and compounds represented by formula (VII): and derivatives thereof.
    Type: Application
    Filed: March 18, 2019
    Publication date: November 25, 2021
    Applicants: MANDOM CORPORATION, OSAKA UNIVERSITY
    Inventors: Kie Nakashima, Ryuichiro Kurata, Fumitaka Fujita, Fumihiro Okada
  • Patent number: 11085916
    Abstract: A method for observing the dynamics of sweat glands and a method for evaluating a substance of interest, which are useful for development of a preparation for external application, such as a cosmetic. In each of the methods, an observation sample is used, which is prepared by staining all sweat glands, which are isolated alive, with a staining reagent, and then holding the all sweat glands on a support using at least one material selected from the group consisting of collagen, agarose, basement membrane matrix, poly-D-lysine and a membrane.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: August 10, 2021
    Assignees: MANDOM CORPORATION, OSAKA UNIVERSITY
    Inventors: Kie Nakashima, Ryuichiro Kurata, Fumitaka Fujita, Kiyotoshi Sekiguchi, Atsushi Tanemura, Hiroyuki Murota, Ichiro Katayama
  • Patent number: 11060061
    Abstract: An immortalized sweat gland myoepithelial cell which expresses ?-SMA and pan-cytokeratin and has a sphere forming ability after subculture at least 5 times. A method for producing immortalized sweat gland myoepithelial said method comprising: while culturing a cell structure, wherein sweat gland myoepithelial cells are exposed on a surface, in a state of being suspended in a medium, transferring an immortalizing gene into the cells; and then culturing the transgenic structure thus obtained in a state of being suspended in the medium to thereby obtain immortalized sweat gland myoepithelial cells.
    Type: Grant
    Filed: August 7, 2018
    Date of Patent: July 13, 2021
    Assignees: MANDOM CORPORATION, OSAKA UNIVERSITY
    Inventors: Tomohisa Hayakawa, Ryuichiro Kurata, Fumitaka Fujita, Fumihiro Okada, Kiyotoshi Sekiguchi
  • Patent number: 11047849
    Abstract: Provided is a method for observing a sebaceous gland, the method making it possible to observe dynamics of a sebaceous gland which dynamics are close to dynamics of a sebaceous gland in a living body. The method includes: an anchoring step of anchoring a sebaceous gland structure to a support so that a sebaceous gland that is included in the sebaceous gland structure and is to be observed and the support are not in biological contact with each other, the sebaceous gland structure being obtained by removing all or part of each of dermis and hypodermis from a skin tissue; and an observation step of observing the sebaceous gland structure obtained in the anchoring step.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: June 29, 2021
    Assignee: MANDOM CORPORATION
    Inventors: Shuta Ishizuka, Ryuichiro Kurata
  • Publication number: 20210003546
    Abstract: Provided is a method whereby an objective indicator of an immune-related disease can be rapidly and easily detected, the method comprising detecting, as an indicator of an immune-related disease, a difference in the result of observing a primary cilium of an immune-related cell between a subject specimen and a normal specimen.
    Type: Application
    Filed: March 8, 2019
    Publication date: January 7, 2021
    Applicants: MANDOM CORPORATION, OSAKA UNIVERSITY, NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION
    Inventors: Manami Toriyama, Fumitaka Fujita, Fumihiro Okada, Ken Ishii
  • Publication number: 20200385680
    Abstract: An immortalized sweat gland myoepithelial cell which expresses ?-SMA and pan-cytokeratin and has a sphere forming ability after subculture at least 5 times. A method for producing immortalized sweat gland myoepithelial said method comprising: while culturing a cell structure, wherein sweat gland myoepithelial cells are exposed on a surface, in a state of being suspended in a medium, transferring an immortalizing gene into the cells; and then culturing the transgenic structure thus obtained in a state of being suspended in the medium to thereby obtain immortalized sweat gland myoepithelial cells.
    Type: Application
    Filed: August 7, 2018
    Publication date: December 10, 2020
    Applicants: MANDOM CORPORATION, OSAKA UNIVERSITY
    Inventors: Tomohisa Hayakawa, Ryuichiro Kurata, Fumitaka Fujita, Fumihiro Okada, Kiyotoshi Sekiguchi
  • Publication number: 20200371090
    Abstract: Provided is a method for observing a sebaceous gland, the method making it possible to observe dynamics of a sebaceous gland which dynamics are close to dynamics of a sebaceous gland in a living body. The method includes: an anchoring step of anchoring a sebaceous gland structure to a support so that a sebaceous gland that is included in the sebaceous gland structure and is to be observed and the support are not in biological contact with each other, the sebaceous gland structure being obtained by removing all or part of each of dermis and hypodermis from a skin tissue; and an observation step of observing the sebaceous gland structure obtained in the anchoring step.
    Type: Application
    Filed: September 5, 2019
    Publication date: November 26, 2020
    Applicant: MANDOM CORPORATION
    Inventors: Shuta Ishizuka, Ryuichiro Kurata
  • Publication number: 20200022889
    Abstract: This TRPA1 activity inhibitor contains a compound represented by formula (I) wherein R1, R2, R3 and R4 each independently represent a hydrogen atom or a methyl group, and R5, R6, R7 and R8 each independently represent a hydrogen atom, a methyl group or —O—R9—OH (in the formula, R9 represents an alkylene group optionally having a substituent group), provided that at least one group of R5, R6, R7 and R8 is —O—R9—OH.
    Type: Application
    Filed: March 13, 2018
    Publication date: January 23, 2020
    Applicants: MANDOM CORPORATION, TAKASAGO INTERNATIONAL CORPORATION
    Inventors: Masayuki Takaishi, Fumitaka Fujita, Hironori Shimizu, Shu Sakuyama, Kenya Ishida, Kenji Maruyama
  • Publication number: 20200003756
    Abstract: A method for observing a sebaceous gland, the method being useful for such applications as developing a cosmetic material or other external preparation, and including (I) a step for culturing, in a suspended state in a medium, a sebaceous gland structure in which the dermis and all or a portion of the subcutaneous tissue is removed from a skin tissue, and (II) a step for observing the cultured sebaceous gland structure obtained in step (I).
    Type: Application
    Filed: February 28, 2018
    Publication date: January 2, 2020
    Applicant: MANDOM CORPORATION
    Inventors: Shuta Ishizuka, Ryuichiro Kurata
  • Publication number: 20190049429
    Abstract: A method for observing the dynamics of sweat glands and a method for evaluating a substance of interest, which are useful for development of a preparation for external application, such as a cosmetic. In each of the methods, an observation sample is used, which is prepared by staining all sweat glands, which are isolated alive, with a staining reagent, and then holding the all sweat glands on a support using at least one material selected from the group consisting of collagen, agarose, basement membrane matrix, poly-D-lysine and a membrane.
    Type: Application
    Filed: July 18, 2017
    Publication date: February 14, 2019
    Applicants: MANDOM CORPORATION, OSAKA UNIVERSITY
    Inventors: Kie Nakashima, Ryuichiro Kurata, Fumitaka Fujita, Kiyotoshi Sekiguchi, Atsushi Tanemura, Hiroyuki Murota, Ichiro Katayama
  • Patent number: 9737467
    Abstract: The present invention provides a body odor suppressing agent that contains activated carbon and that has excellent body odor suppressing effects, causes no black soiling on an object to be coated, and has excellent practical aptitude. The present invention also provides a body odor suppressing agent having an excellent feeling of use when the agent is applied to the skin. The present invention further provides a body odor suppressing agent capable of preventing nozzles from clogging when the agent is packed into a spray container and used. The body odor suppressing agent of the present invention includes a titanium oxide-coated activated carbon including an activated carbon having an average particle diameter of 15 to 50 ?m and a titanium oxide present over the surface of the activated carbon.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: August 22, 2017
    Assignee: MANDOM CORPORATION
    Inventors: Takeshi Hara, Hironori Shimizu
  • Patent number: 8992894
    Abstract: An oral stain remover which can remove a stain or a dental plaque effectively without a need of brushing the surface of teeth with a toothbrush or the like, and an oral composition containing the stain remover. An oral stain remover contains a salt of ultraphosphoric acid, and an oral composition contains the oral stain remover.
    Type: Grant
    Filed: June 14, 2007
    Date of Patent: March 31, 2015
    Assignees: Mandom Corporation, REGENETISS Inc.
    Inventors: Toshikazu Shiba, Atsushi Saitou, Kazuyoshi Okada, Yoshio Tsujino
  • Publication number: 20150013712
    Abstract: The present invention provides a powdery solid hair cosmetic that enables easy hairdressing, enables hairdressing into an intended hairstyle without sticky feeling, can impart a natural texture, and has an unprecedented, novel form. The powdery solid composition for hair of the present invention is in a powdery solid form, is used for hair, and contains a powder and an oil.
    Type: Application
    Filed: March 27, 2013
    Publication date: January 15, 2015
    Applicant: MANDOM CORPORATION
    Inventors: Takeharu Ishii, Takuji Asada
  • Patent number: 7939307
    Abstract: Modified CueO having excellent enzymatic activity and a composition for dyeing keratin fiber which contains the enzyme. A recombinant protein having an enzymatic activity for oxidizing p-phenylenediamine, the protein is obtained by removing from CueO at least one member selected from the group consisting of helix 5, helix 6, and helix 7; and the composition for dyeing keratin fiber containing the recombinant protein and an oxidation dye.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: May 10, 2011
    Assignees: National University Corporation Kanazawa University, Mandom Corporation
    Inventors: Kaori Otsuka, Yoshio Tsujino, Yusuke Konno, Shinji Kurose, Kunishige Kataoka, Takeshi Sakurai
  • Publication number: 20100205754
    Abstract: Modified CueO having excellent enzymatic activity and a composition for dyeing keratin fiber which contains the enzyme. A recombinant protein having an enzymatic activity for oxidizing p-phenylenediamine, the protein is obtained by removing from CueO at least one member selected from the group consisting of helix 5, helix 6, and helix 7; and the composition for dyeing keratin fiber containing the recombinant protein and an oxidation dye.
    Type: Application
    Filed: April 14, 2006
    Publication date: August 19, 2010
    Applicants: NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSIT, MANDOM CORPORATION
    Inventors: Kaori Otsuka, Yoshio Tsujino, Yusuke Konno, Shinji Kurose, Kunishige Kataoka, Takeshi Sakurai
  • Patent number: 7754774
    Abstract: The purpose of the present invention is to provide antiseptic disinfectant, and cosmetics and toiletries, medicine or food containing the same, which enhance the antibacterial activity that 1,2-alkanediol originally have against a broad range of strains by compounding 1,2-alkanediol with 5-10 carbons and a certain fragrance component. The present invention relates to an antiseptic disinfectant, and cosmetics and toiletries, medicine or food containing the same, which include 1,2-alkanediol with 5-10 carbons, and one or more materials selected from a group of thymol, eugenol, citronellal, terpinyl acetate, citronellol and ?-pinene.
    Type: Grant
    Filed: September 25, 2003
    Date of Patent: July 13, 2010
    Assignee: Mandom Corporation
    Inventors: Aki Kobayashi, Hiroya Okamoto, Fumihiro Okada
  • Patent number: 7632871
    Abstract: The present invention relates to methods for producing and using antiseptic disinfectant, cosmetic and toiletries, medicine or food and method for antiseptically disinfecting a cosmetic and toiletries, medicine or food. The cosmetic and toiletries, medicine or food contain an antiseptic disinfectant comprising 1,2-alkanediol with 5-10 carbons and a fragrance component, and the fragrance component enhances the antibacterial activity that the 1,2-alkanediol originally has against a broad range of strains.
    Type: Grant
    Filed: May 19, 2006
    Date of Patent: December 15, 2009
    Assignee: Mandom Corporation
    Inventors: Aki Kobayashi, Hiroya Okamoto, Fumihiro Okada
  • Publication number: 20090280072
    Abstract: An oral stain remover which can remove a stain or a dental plaque effectively without a need of brushing the surface of teeth with a toothbrush or the like, and an oral composition containing the stain remover. An oral stain remover contains a salt of ultraphosphoric acid, and an oral composition contains the oral stain remover.
    Type: Application
    Filed: June 14, 2007
    Publication date: November 12, 2009
    Applicant: MANDOM CORPORATION
    Inventors: Toshikazu Shiba, Atsushi Saitou, Kazuyoshi Okada, Yoshio Tsujino