Patents Assigned to Manfred FREY
  • POLYNUCLEOTIDES FOR ENHANCING EXPRESSION OF A POLYNUCLEOTIDE OF INTEREST
    Publication number: 20100113574
    Abstract: The present invention relates to polynucleotides comprising a first nucleic acid sequence for a chromatin element, which is capable of enhancing expression, and at least one second nucleic acid sequence comprising a curved origin motif. Furthermore, the invention relates to a host cell, a non-human transgenic organism, a vector and a kit comprising the aforementioned polynucleotide. Moreover, the invention relates to methods for expressing a polynucleotide of interest.
    Type: Application
    Filed: March 28, 2008
    Publication date: May 6, 2010
    Applicants: Manfred FREY, Hochschule Mannheim
    Inventors: Manfred Frey, Heiko Flammann, Mathias Hafner