Patents Assigned to MannKing Corporation
  • IRE-1? inhibitors
    Patent number: 9493435
    Abstract: The invention provides compounds which directly inhibit IRE-1? activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response and can be used as single agents or in combination therapies.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: November 15, 2016
    Assignee: MannKing Corporation
    Inventors: Qingping Zeng, Warren S. Wade, John Bruce Patterson