Abstract: The present invention relates to processes for the preparation of deferasirox, an oral iron chelator developed to treat iron overload due to e.g. multiple blood transfusions. The present invention further provides novel deferasirox pseudopolymorphs and a novel amorphous form of deferasirox, processes for their preparation, as well as pharmaceutical compositions comprising same, and use thereof in treating iron overload.
Type:
Application
Filed:
January 28, 2010
Publication date:
September 27, 2012
Applicant:
MAPI PHARMA HK LIMITED
Inventors:
Michael Mizhiritskii, Ehud Marom, Shai Rubnov