Abstract: The compositions described herein and featured in the present invention include those that comprise anthocyanidin combinations rich in delphinidins, including delphinidins such as the ones found in berries. The compositions can optionally include either compositions that comprise andrographolides, such as the ones found in a plant of the genus Andrographis, or compositions that comprise combinations of myrtillin, quercetin, or caffeoyl quinic derivatives and proanthocyanidins, such as the ones found in the herba of a plant of the genus Vaccinium.
Type:
Application
Filed:
January 24, 2019
Publication date:
May 23, 2019
Applicant:
MAQUI NEW LIFE S.A.
Inventors:
Rafael Burgos, Juan Hancke, Evelyn Jara, Maria Hidalgo
Abstract: The present invention relates to methods for decreasing intestinal glucose uptake and inducing incretin release in a human subject, entailing the activation of human G protein-coupled receptor GPR40 (a receptor expressed in human intestinal L-cells) by administering one or more anthocyanin or anthocyanidin compounds, preferably one or more delphinidin compounds, in an amount effective for the activation of GPR40 and the induction of incretin.
Type:
Application
Filed:
October 30, 2013
Publication date:
May 8, 2014
Applicant:
MAQUI NEW LIFE S.A.
Inventors:
Juan Luis HANCKE OROZCO, Rafael Agustin BURGOS AGUILERA, Evelyn Liliana JARA FERNANDEZ