Abstract: Water-insoluble, tridimensional cross-linked random copolymers, which contain in copolymerized form:(a) 25% to 98% by weight of N-[tris(hydroxymethyl)methyl]acrylamide or N-[tris(hydroxymethyl)methyl]methacrylamide or a mixture of these two compounds;(b) 2% to 50% by weight of one or more monomers having several polymerizable ethylenic double bonds and one or more hydroxy groups, and free from NH.sub.2 or COOH groups; and(c) 0% to 50% by weight of one or more monomers having a polymerizable ethylenic double bond and one or more amino or carboxy groups. These copolymers may be used, in the form of aqueous gels, as supports in techniques of separation such as gell permeation chromatography and in techniques of immobilization of natural substances.
Type:
Grant
Filed:
January 27, 1978
Date of Patent:
March 11, 1980
Assignee:
Mar-Pha Societe d'Etudes et d'Exploitation de Marques
Inventors:
Eric Brown, Egisto Boschetti, Monique M. Corgier, Joel Touet
Abstract: 1-ISOPROPYLAMINO-3-[2-(2-NORBORNYL EXO)PHENOXY]PROPAN-2-OL, ITS 1-ISOPROPYLAMINO-3-[2-NORBORNYL ENDO)PHENOXY]PROPAN-2-OL ISOMER AND THEIR ACID ADDITION SALTS AND THEIR QUATERNARY AMMONIUM SALTS.These compounds can be used as beta-blocking agents against disorders of the cardiac rhythm, anti-anxiety and anti-hypertension medicaments.
Type:
Grant
Filed:
August 8, 1977
Date of Patent:
June 5, 1979
Assignee:
MAR-PHA, Societe d'Etude et d'Exploitation de Marques
Abstract: New terpenophenols of the general formula: ##STR1## wherein R is a 2-isobornyl, 5-camphyl or 2-norbornyl group of exo or endo configuration and in the ortho, meta or para position with respect to the OH group; R.sub.1, R.sub.2 may each be a hydrogen atom or halogen atom (Cl, Br, F,I) or a lower alkyl or lower alkoxy radical having a straight or branched chain of 1 to 4 carbon atoms or a nitro or cyano group.
Type:
Grant
Filed:
June 6, 1977
Date of Patent:
September 5, 1978
Assignee:
MAR-PHA, Societe d'Etude et d'Exploitation de Marques
Abstract: New terpenophenols of the general formula: ##STR1## wherein R is a 2-isobornyl, 5-camphyl or 2-norbornyl group of exo or endo configuration and in the ortho, meta or para position with respect to the OH group; R.sub.1, R.sub.2 may each be a hydrogen atom or halogen atom (Cl, Br, F, I) or a lower alkyl or lower alkoxy radical having a straight or branched chain of 1 to 4 carbon atoms or a nitro or cyano group.
Type:
Grant
Filed:
April 9, 1975
Date of Patent:
January 10, 1978
Assignee:
Societe Anonyme dite: MAR-PHA, Societe d'Etude et d'Exploitation de Marques
Abstract: Compounds of the general formula ##STR1## wherein R.sub.1 and R.sub.3 represent hydrogen or alkyl containing 1 to 4 carbons; R.sub.2 and R.sub.4 represent hydrogen, alkyl containing 1 to 8 carbons, dialkylaminoalkyl or aryl, ##STR2## may also represent the piperazinyl group which may be substituted in the 4 position by methyl, phenyl or benzyl.Compounds have pharmaceutical utility.
Type:
Grant
Filed:
May 20, 1976
Date of Patent:
September 27, 1977
Assignee:
Mar-Pha Societe d'Etudes et d'Exploitation de Marques
Inventors:
Georges Dominique Mattioda, Francois Louis Albert Rocquet