Abstract: Spontaneously dispersible concentrates capable of forming ultramicroemulsions are described. The concentrates include esters of formula (I) and (II):
wherein (a) R1, R3, R4, and R5 each independently represents a C6-22 alkyl, a C6-22 alkenyl or a C6-22 alkapolyene and R2 is glucose:(1,2); (b) R2, R3, R4, and R5 each independently represents a C6-22 alkyl, a C6-22 alkenyl or a C6-22 alkapolyene and R1 is glucose:(1,3); (c) R2, R3, R4, and R5 each independently represents a C6-22 alkyl, a C6-22 alkenyl or a C6-22 alkapolyene and R1 is rhamnose:(1,4); or (d) R2, R3, R4, and R5 each independently represents a C6-22 alkyl, a C6-22 alkenyl or a C6-22 alkapolyene and R1 is rutinose:(1,5);
wherein
(a) R1, R2, and R4 each independently represents a C6-22 alkyl, a C6-22 alkenyl or a C6-22 alkapolyene and R3 is rhamnose:(11,7); or (b) R2 and R4 each independently represents a C6-22 alkyl, a C6-22 alkenyl or a C6-22 alkapolyene, R1 is methyl, and R3 is rutinose:(11,8).
Abstract: New biotenside esters and phosphatides formed with Vitamin-D and Vitamin-E compounds possessing a pronounced antitumor activity, processes for their production as well as for the preparation of concentrates and pharmaceutical compositions containing these new esters and phosphatides, and their use for treating tumors are described.
Type:
Grant
Filed:
September 30, 1994
Date of Patent:
March 26, 1996
Assignee:
Marigen, S.A.
Inventors:
Carl Eugster, Conrad H. Eugster, Walter Haldemann, Giorgio Rivara