Abstract: A biological fluid measuring device for determining the presence and the amounts of substances in a biological fluid without the need for dilution of the fluid comprises a main housing including electronic circuit means and at least one electrode, and a cartridge having a membrane. The cartridge is removably mounted on the housing and the membrane is maintained operably associated by osmotic pressure with the electrode. The cartridge also includes means for protecting the membrane when the device is not in use. An enzyme electrode is also disclosed comprising a multilayered homogeneous monolithic membrane and an intermediate water-swellable coating.
Type:
Grant
Filed:
July 7, 1988
Date of Patent:
February 19, 1991
Assignee:
Markwell Medical Institute, Inc.
Inventors:
Mark G. Shults, Christopher C. Capelli, Stuart J. Updike
Abstract: A biological fluid measuring device for determining the presence and the amounts of substances in a biological fluid without the need for dilution of the fluid comprises a main housing including electronic circuit means and at least one elecrode, and a cartridge having a membrane. The cartridge is removably mounted on the housing and the membrane is operably associated with the electrode. The cartridge also includes means for protecting the membrane when the device is not in use.
Type:
Grant
Filed:
November 19, 1987
Date of Patent:
July 12, 1988
Assignee:
Markwell Medical Institute, Inc.
Inventors:
Mark C. Shults, Christopher C. Capelli, Stuart J. Updike
Abstract: A device comprising a container and a threaded rotatable plunger mechanism including means for controllably advancing the plunger through the container can administer a precise dose of a drug-containing fluid subcutaneously at regular intervals. The means for controllably advancing the plunger comprises a drive tube concentrically mounted about a threaded rod operating within the container, the drive tube having ramp means at the upper end thereof, a ratchet head including a resilient member in operative communication with the upper end of the drive tube and a rotatable knob adjacent the ratchet head whereby rotation of the knob in one direction rotates the drive tube and the threaded rod to deliver the fluid through an outlet of the container.