Patents Assigned to MARUHA NICHIRO CORPORATION
  • Publication number: 20210275486
    Abstract: Provided is a renal function maintenance and protection agent comprising as an active ingredient of a triglyceride of docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) or a mixture of a triglyceride of docosahexaenoic acid (DHA) and a triglyceride of eicosapentaenoic acid (EPA), which can be used as a pharmaceutical or food composition. A triglyceride of docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) or a mixture of a triglyceride of docosahexaenoic acid (DHA) and a triglyceride of eicosapentaenoic acid (EPA) is used as an active ingredient for renal function maintenance and protection agents.
    Type: Application
    Filed: July 19, 2019
    Publication date: September 9, 2021
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Masataka KAWARASAKI, Yosuke CHIBA, Akira KAMATA, Tomoaki HASHIMOTO, Yoichiro SHIRAHAMA
  • Patent number: 11051540
    Abstract: A shrimp-like food has mannan-containing fibrous portions and a mannan-containing binding portion binding between the fibrous portions. The fibrous portions are preferably arranged in a random orientation in the food. The fibrous portions preferably have a thickness of 0.8 to 3.0 mm. The mannan contents in the fibrous and binding portions are both preferably 1 to 7 mass %.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: July 6, 2021
    Assignee: MARUHA NICHIRO CORPORATION
    Inventors: Wataru Hashigaya, Naoki Honda, Mitsuru Hosokawa
  • Patent number: 10813914
    Abstract: A composition for controlling or preventing microsporidia in a fish or a seafood is prepared by using, as an active ingredient, at least one compound selected from the group consisting of compounds represented by the following chemical formula (I): (wherein, R2, R4, R5, R6 and R7 each independently represent a specific substituent), pharmaceutically acceptable salts thereof, and compounds generating the compounds represented by the chemical formula (I) by metabolism in the body of the fish or the seafood. By using this composition for controlling or preventing microsporidia in a fish to or a seafood, a method for controlling or preventing microsporidia in a fish or a seafood is provided, which prevents microsporidian infection in the muscle or organs of the fish or the seafood, and/or suppresses the growth of microsporidia in the muscle or organs of the fish or the seafood, and/or highly effective in eliminating microsporidia from the body of the fish or the seafood and also excellent in safety.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: October 27, 2020
    Assignees: MARUHA NICHIRO CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Yukitoki Fujita, Hiroshi Yokoyama, Hiroki Ogawa
  • Publication number: 20200038479
    Abstract: An object of the present invention is to provide an active ingredient for a wound healing agent that has high biocompatibility and an antimicrobial activity, as well as a wound healing accelerating activity, which can be applied to supply of a wound healing agent comprising a single active ingredient, which can be produced by a simple production process and production apparatus. According to the present invention, at least one compound selected from a protamine and pharmaceutically acceptable salts thereof is used as an active ingredient for antibacterial activity and wound healing acceleration of a wound healing agent.
    Type: Application
    Filed: October 4, 2017
    Publication date: February 6, 2020
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Hiroyuki ENARI, Keishi IOHARA, Akira KAMATA, Daisuke KOIZUMI
  • Patent number: 10513538
    Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: December 24, 2019
    Assignee: MARUHA NICHIRO CORPORATION
    Inventors: Yoshinori Takahashi, Akira Kamata, Tatsuya Konishi
  • Patent number: 10433570
    Abstract: According to the present invention, a method for recovering useful fish meat proteins from waste water generated during fish paste or fishmeal production is provided. The provided is a method for recovering water-soluble proteins from fish paste leaching waste water or stick water, comprising: adjusting the pH of fish paste leaching waste water or stick water to 4.5-5.5 to insolubilize water-soluble proteins; heating the insolubilized proteins to 30° C. to 90° C. to cause the proteins to flocculate so as to form flocs; subjecting the flocs to solid-liquid separation using a decanter centrifuge during heating; and recovering proteins in the form of solid content.
    Type: Grant
    Filed: August 8, 2014
    Date of Patent: October 8, 2019
    Assignee: MARUHA NICHIRO CORPORATION
    Inventors: Kazuya Shirota, Ryusuke Nakashima, Shin-ichiro Nishimoto, Kenji Funaki, Takeshi Suzuki, Itaru Kawada
  • Publication number: 20190111027
    Abstract: A composition for controlling or preventing microsporidia in a fish or a seafood is prepared by using, as an active ingredient, at least one compound selected from the group consisting of compounds represented by the following chemical formula (I): (wherein, R2, R4, R5, R6 and R7 each independently represent a specific substituent), pharmaceutically acceptable salts thereof, and compounds generating the compounds represented by the chemical formula (I) by metabolism in the body of the fish or the seafood. By using this composition for controlling or preventing microsporidia in a fish to or a seafood, a method for controlling or preventing microsporidia in a fish or a seafood is provided, which prevents microsporidian infection in the muscle or organs of the fish or the seafood, and/or suppresses the growth of microsporidia in the muscle or organs of the fish or the seafood, and/or highly effective in eliminating microsporidia from the body of the fish or the seafood and also excellent in safety.
    Type: Application
    Filed: March 30, 2017
    Publication date: April 18, 2019
    Applicants: MARUHA NICHIRO CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Yukitoki FUJITA, Hiroshi YOKOYAMA, Hiroki OGAWA
  • Patent number: 10166313
    Abstract: A bone-repairing agent excellent in workability and applicability to clinical surgical techniques and having a drastically enhanced bone formation rate, obtained by including an elastin hydrolysate in a complex of DNA and at least one selected from the group consisting of protamine, a protamine derivative, and a protamine hydrolysate can be provided. A medical or dental material for bone formation using this bone-repairing agent can be provided.
    Type: Grant
    Filed: September 25, 2013
    Date of Patent: January 1, 2019
    Assignee: MARUHA NICHIRO CORPORATION
    Inventors: Tadao Fukushima, Jun Yamazaki, Jun Ohno, Masako Toda, Makoto Mitarai, Keishi Iohara
  • Publication number: 20180110748
    Abstract: A composition which can efficiently obtain an effect of decreasing or suppressing an increase in the neutral fat level is provided. Docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA) is used as an active ingredient of a composition for decreasing or suppressing an increase in the neutral fat level, and the timing of intake of the active ingredient is within a time for intake within 6 hours after arousal from sleep including the breakfast time essentially including the breakfast time.
    Type: Application
    Filed: October 20, 2017
    Publication date: April 26, 2018
    Applicants: MARUHA NICHIRO CORPORATION, National Institute of Advanced Industrial Science and Technology
    Inventors: Tatsuya Konishi, Yasuhiko Shiina, Yoshinori Takahashi, Katsutaka Oishi, Chiaki Hasimoto, Saori Yamamoto
  • Publication number: 20180094027
    Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.
    Type: Application
    Filed: December 8, 2017
    Publication date: April 5, 2018
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Yoshinori Takahashi, Akira Kamata, Tatsuya Konishi
  • Patent number: 9868764
    Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: January 16, 2018
    Assignee: Maruha Nichiro Corporation
    Inventors: Yoshinori Takahashi, Akira Kamata, Tatsuya Konishi
  • Publication number: 20170354177
    Abstract: A composition with an enhanced antifungal activity, which comprises peptides as a protamine hydrolysate and which is suitable for industrial application at a low cost, can be provided, by using a combination of a protamine hydrolysate and a terpene alcohol as an active ingredient of a composition having an antifungal activity.
    Type: Application
    Filed: September 1, 2015
    Publication date: December 14, 2017
    Applicants: MARUHA NICHIRO CORPORATION, TEIKYO UNIVERSITY
    Inventors: Keishi IOHARA, Makoto MITARAI, Shigeru ABE, Kazumi HAYAMA
  • Publication number: 20170211037
    Abstract: The present invention aims to provide methods for producing brown algae or brown algal extracts of reduced iodine content while retaining the structures of pigment components in the brown algae. Provided is a method for producing a brown alga of reduced iodine content while retaining a pigment component in the brown alga, which method comprises shredding an untreated brown algal starting material and thereafter performing a heating treatment with hot water at 90-100° C. for 90-300 seconds. Also provided is a method for producing a brown alga of reduced iodine content while retaining a pigment component in the brown alga, wherein the brown alga obtained in the above-mentioned process is subjected to extraction using hydrous ethanol at a concentration of 60-100%.
    Type: Application
    Filed: September 29, 2015
    Publication date: July 27, 2017
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Yosuke CHIBA, Hisashi YOSHIOKA, Takumi DAIMON, Hiroshi ODA, Masahiko SHIMADA, Kuniaki TATSUTA
  • Publication number: 20170189377
    Abstract: Degranulation suppressors are provided that are effective against allergic disease and osteoarthritis. The degranulation suppressors contain chlorophyll c.
    Type: Application
    Filed: March 7, 2017
    Publication date: July 6, 2017
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Hisashi YOSHIOKA, Akira KAMATA, Tatsuya KONISHI, Hiroshi ODA, Tadakazu TAMAI
  • Patent number: 9693996
    Abstract: Degranulation suppressors are provided that are effective against allergic disease and osteoarthritis. The degranulation suppressors contain chlorophyll c.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: July 4, 2017
    Assignee: MARUHA NICHIRO CORPORATION
    Inventors: Hisashi Yoshioka, Akira Kamata, Tatsuya Konishi, Hiroshi Oda, Tadakazu Tamai
  • Patent number: 9636326
    Abstract: Degranulation suppressors are provided that are effective against allergic disease and osteoarthritis. The degranulation suppressors contain chlorophyll c.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: May 2, 2017
    Assignee: MARUHA NICHIRO CORPORATION
    Inventors: Hisashi Yoshioka, Akira Kamata, Tatsuya Konishi, Hiroshi Oda, Tadakazu Tamai
  • Patent number: 9486496
    Abstract: A medical or dental material can be prepared by using, as an active ingredient, at least one of a protamine, and derivatives thereof and hydrolysates thereof, or a complex of at least one of a protamine, and derivatives thereof and hydrolysates thereof with an anionic high molecular weight compound. As a result, an antibacterial agent against periodontal disease-causing bacteria can be provided, which is highly safe without concern of a side effect. A medical or dental material can be also provided, which exhibits antimicrobial activity on periodontal disease-causing bacteria and additionally has insolubility in water and good formability.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: November 8, 2016
    Assignees: MARUHA NICHIRO CORPORATION
    Inventors: Tadao Fukushima, Tohru Hayakawa, Yoshio Okahata, Makoto Mitarai, Keishi Iohara, Hiroyuki Enari, Haruchika Sekido
  • Publication number: 20160235888
    Abstract: A bone-repairing agent excellent in workability and applicability to clinical surgical techniques and having a drastically enhanced bone formation rate, obtained by including an elastin hydrolysate in a complex of DNA and at least one selected from the group consisting of protamine, a protamine derivative, and a protamine hydrolysate can be provided. A medical or dental material for bone formation using this bone-repairing agent can be provided.
    Type: Application
    Filed: September 25, 2013
    Publication date: August 18, 2016
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Tadao FUKUSHIMA, Jun YAMAZAKI, Jun OHNO, Masako TODA, Makoto MITARAI, Keishi IOHARA
  • Publication number: 20160198737
    Abstract: According to the present invention, a method for recovering useful fish meat proteins from waste water generated during fish paste or fishmeal production is provided. The provided is a method for recovering water-soluble proteins from fish paste leaching waste water or stick water, comprising: adjusting the pH of fish paste leaching waste water or stick water to 4.5-5.5 to insolubilize water-soluble proteins; heating the insolubilized proteins to 30° C. to 90° C. to cause the proteins to flocculate so as to form flocs; subjecting the flocs to solid-liquid separation using a decanter centrifuge during heating; and recovering proteins in the form of solid content.
    Type: Application
    Filed: August 8, 2014
    Publication date: July 14, 2016
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Kazuya SHIROTA, Ryusuke NAKASHIMA, Shin-ichiro NISHIMOTO, Kenji FUNAKI, Takeshi SUZUKI, Itaru KAWADA
  • Publication number: 20160194355
    Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.
    Type: Application
    Filed: May 19, 2014
    Publication date: July 7, 2016
    Applicant: MARUHA NICHIRO CORPORATION
    Inventors: Yoshinori TAKAHASHI, Akira KAMATA, Tatsuya KONISHI