Patents Assigned to MARUHA NICHIRO CORPORATION
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Publication number: 20210275486Abstract: Provided is a renal function maintenance and protection agent comprising as an active ingredient of a triglyceride of docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) or a mixture of a triglyceride of docosahexaenoic acid (DHA) and a triglyceride of eicosapentaenoic acid (EPA), which can be used as a pharmaceutical or food composition. A triglyceride of docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) or a mixture of a triglyceride of docosahexaenoic acid (DHA) and a triglyceride of eicosapentaenoic acid (EPA) is used as an active ingredient for renal function maintenance and protection agents.Type: ApplicationFiled: July 19, 2019Publication date: September 9, 2021Applicant: MARUHA NICHIRO CORPORATIONInventors: Masataka KAWARASAKI, Yosuke CHIBA, Akira KAMATA, Tomoaki HASHIMOTO, Yoichiro SHIRAHAMA
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Patent number: 11051540Abstract: A shrimp-like food has mannan-containing fibrous portions and a mannan-containing binding portion binding between the fibrous portions. The fibrous portions are preferably arranged in a random orientation in the food. The fibrous portions preferably have a thickness of 0.8 to 3.0 mm. The mannan contents in the fibrous and binding portions are both preferably 1 to 7 mass %.Type: GrantFiled: March 8, 2017Date of Patent: July 6, 2021Assignee: MARUHA NICHIRO CORPORATIONInventors: Wataru Hashigaya, Naoki Honda, Mitsuru Hosokawa
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Patent number: 10813914Abstract: A composition for controlling or preventing microsporidia in a fish or a seafood is prepared by using, as an active ingredient, at least one compound selected from the group consisting of compounds represented by the following chemical formula (I): (wherein, R2, R4, R5, R6 and R7 each independently represent a specific substituent), pharmaceutically acceptable salts thereof, and compounds generating the compounds represented by the chemical formula (I) by metabolism in the body of the fish or the seafood. By using this composition for controlling or preventing microsporidia in a fish to or a seafood, a method for controlling or preventing microsporidia in a fish or a seafood is provided, which prevents microsporidian infection in the muscle or organs of the fish or the seafood, and/or suppresses the growth of microsporidia in the muscle or organs of the fish or the seafood, and/or highly effective in eliminating microsporidia from the body of the fish or the seafood and also excellent in safety.Type: GrantFiled: March 30, 2017Date of Patent: October 27, 2020Assignees: MARUHA NICHIRO CORPORATION, THE UNIVERSITY OF TOKYOInventors: Yukitoki Fujita, Hiroshi Yokoyama, Hiroki Ogawa
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Publication number: 20200038479Abstract: An object of the present invention is to provide an active ingredient for a wound healing agent that has high biocompatibility and an antimicrobial activity, as well as a wound healing accelerating activity, which can be applied to supply of a wound healing agent comprising a single active ingredient, which can be produced by a simple production process and production apparatus. According to the present invention, at least one compound selected from a protamine and pharmaceutically acceptable salts thereof is used as an active ingredient for antibacterial activity and wound healing acceleration of a wound healing agent.Type: ApplicationFiled: October 4, 2017Publication date: February 6, 2020Applicant: MARUHA NICHIRO CORPORATIONInventors: Hiroyuki ENARI, Keishi IOHARA, Akira KAMATA, Daisuke KOIZUMI
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Patent number: 10513538Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.Type: GrantFiled: December 8, 2017Date of Patent: December 24, 2019Assignee: MARUHA NICHIRO CORPORATIONInventors: Yoshinori Takahashi, Akira Kamata, Tatsuya Konishi
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Patent number: 10433570Abstract: According to the present invention, a method for recovering useful fish meat proteins from waste water generated during fish paste or fishmeal production is provided. The provided is a method for recovering water-soluble proteins from fish paste leaching waste water or stick water, comprising: adjusting the pH of fish paste leaching waste water or stick water to 4.5-5.5 to insolubilize water-soluble proteins; heating the insolubilized proteins to 30° C. to 90° C. to cause the proteins to flocculate so as to form flocs; subjecting the flocs to solid-liquid separation using a decanter centrifuge during heating; and recovering proteins in the form of solid content.Type: GrantFiled: August 8, 2014Date of Patent: October 8, 2019Assignee: MARUHA NICHIRO CORPORATIONInventors: Kazuya Shirota, Ryusuke Nakashima, Shin-ichiro Nishimoto, Kenji Funaki, Takeshi Suzuki, Itaru Kawada
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Publication number: 20190111027Abstract: A composition for controlling or preventing microsporidia in a fish or a seafood is prepared by using, as an active ingredient, at least one compound selected from the group consisting of compounds represented by the following chemical formula (I): (wherein, R2, R4, R5, R6 and R7 each independently represent a specific substituent), pharmaceutically acceptable salts thereof, and compounds generating the compounds represented by the chemical formula (I) by metabolism in the body of the fish or the seafood. By using this composition for controlling or preventing microsporidia in a fish to or a seafood, a method for controlling or preventing microsporidia in a fish or a seafood is provided, which prevents microsporidian infection in the muscle or organs of the fish or the seafood, and/or suppresses the growth of microsporidia in the muscle or organs of the fish or the seafood, and/or highly effective in eliminating microsporidia from the body of the fish or the seafood and also excellent in safety.Type: ApplicationFiled: March 30, 2017Publication date: April 18, 2019Applicants: MARUHA NICHIRO CORPORATION, THE UNIVERSITY OF TOKYOInventors: Yukitoki FUJITA, Hiroshi YOKOYAMA, Hiroki OGAWA
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Patent number: 10166313Abstract: A bone-repairing agent excellent in workability and applicability to clinical surgical techniques and having a drastically enhanced bone formation rate, obtained by including an elastin hydrolysate in a complex of DNA and at least one selected from the group consisting of protamine, a protamine derivative, and a protamine hydrolysate can be provided. A medical or dental material for bone formation using this bone-repairing agent can be provided.Type: GrantFiled: September 25, 2013Date of Patent: January 1, 2019Assignee: MARUHA NICHIRO CORPORATIONInventors: Tadao Fukushima, Jun Yamazaki, Jun Ohno, Masako Toda, Makoto Mitarai, Keishi Iohara
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Publication number: 20180110748Abstract: A composition which can efficiently obtain an effect of decreasing or suppressing an increase in the neutral fat level is provided. Docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA) is used as an active ingredient of a composition for decreasing or suppressing an increase in the neutral fat level, and the timing of intake of the active ingredient is within a time for intake within 6 hours after arousal from sleep including the breakfast time essentially including the breakfast time.Type: ApplicationFiled: October 20, 2017Publication date: April 26, 2018Applicants: MARUHA NICHIRO CORPORATION, National Institute of Advanced Industrial Science and TechnologyInventors: Tatsuya Konishi, Yasuhiko Shiina, Yoshinori Takahashi, Katsutaka Oishi, Chiaki Hasimoto, Saori Yamamoto
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Publication number: 20180094027Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.Type: ApplicationFiled: December 8, 2017Publication date: April 5, 2018Applicant: MARUHA NICHIRO CORPORATIONInventors: Yoshinori Takahashi, Akira Kamata, Tatsuya Konishi
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Patent number: 9868764Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.Type: GrantFiled: May 19, 2014Date of Patent: January 16, 2018Assignee: Maruha Nichiro CorporationInventors: Yoshinori Takahashi, Akira Kamata, Tatsuya Konishi
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Publication number: 20170354177Abstract: A composition with an enhanced antifungal activity, which comprises peptides as a protamine hydrolysate and which is suitable for industrial application at a low cost, can be provided, by using a combination of a protamine hydrolysate and a terpene alcohol as an active ingredient of a composition having an antifungal activity.Type: ApplicationFiled: September 1, 2015Publication date: December 14, 2017Applicants: MARUHA NICHIRO CORPORATION, TEIKYO UNIVERSITYInventors: Keishi IOHARA, Makoto MITARAI, Shigeru ABE, Kazumi HAYAMA
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Publication number: 20170211037Abstract: The present invention aims to provide methods for producing brown algae or brown algal extracts of reduced iodine content while retaining the structures of pigment components in the brown algae. Provided is a method for producing a brown alga of reduced iodine content while retaining a pigment component in the brown alga, which method comprises shredding an untreated brown algal starting material and thereafter performing a heating treatment with hot water at 90-100° C. for 90-300 seconds. Also provided is a method for producing a brown alga of reduced iodine content while retaining a pigment component in the brown alga, wherein the brown alga obtained in the above-mentioned process is subjected to extraction using hydrous ethanol at a concentration of 60-100%.Type: ApplicationFiled: September 29, 2015Publication date: July 27, 2017Applicant: MARUHA NICHIRO CORPORATIONInventors: Yosuke CHIBA, Hisashi YOSHIOKA, Takumi DAIMON, Hiroshi ODA, Masahiko SHIMADA, Kuniaki TATSUTA
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Publication number: 20170189377Abstract: Degranulation suppressors are provided that are effective against allergic disease and osteoarthritis. The degranulation suppressors contain chlorophyll c.Type: ApplicationFiled: March 7, 2017Publication date: July 6, 2017Applicant: MARUHA NICHIRO CORPORATIONInventors: Hisashi YOSHIOKA, Akira KAMATA, Tatsuya KONISHI, Hiroshi ODA, Tadakazu TAMAI
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Patent number: 9693996Abstract: Degranulation suppressors are provided that are effective against allergic disease and osteoarthritis. The degranulation suppressors contain chlorophyll c.Type: GrantFiled: March 7, 2017Date of Patent: July 4, 2017Assignee: MARUHA NICHIRO CORPORATIONInventors: Hisashi Yoshioka, Akira Kamata, Tatsuya Konishi, Hiroshi Oda, Tadakazu Tamai
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Patent number: 9636326Abstract: Degranulation suppressors are provided that are effective against allergic disease and osteoarthritis. The degranulation suppressors contain chlorophyll c.Type: GrantFiled: December 28, 2012Date of Patent: May 2, 2017Assignee: MARUHA NICHIRO CORPORATIONInventors: Hisashi Yoshioka, Akira Kamata, Tatsuya Konishi, Hiroshi Oda, Tadakazu Tamai
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Patent number: 9486496Abstract: A medical or dental material can be prepared by using, as an active ingredient, at least one of a protamine, and derivatives thereof and hydrolysates thereof, or a complex of at least one of a protamine, and derivatives thereof and hydrolysates thereof with an anionic high molecular weight compound. As a result, an antibacterial agent against periodontal disease-causing bacteria can be provided, which is highly safe without concern of a side effect. A medical or dental material can be also provided, which exhibits antimicrobial activity on periodontal disease-causing bacteria and additionally has insolubility in water and good formability.Type: GrantFiled: December 21, 2009Date of Patent: November 8, 2016Assignees: MARUHA NICHIRO CORPORATIONInventors: Tadao Fukushima, Tohru Hayakawa, Yoshio Okahata, Makoto Mitarai, Keishi Iohara, Hiroyuki Enari, Haruchika Sekido
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Publication number: 20160235888Abstract: A bone-repairing agent excellent in workability and applicability to clinical surgical techniques and having a drastically enhanced bone formation rate, obtained by including an elastin hydrolysate in a complex of DNA and at least one selected from the group consisting of protamine, a protamine derivative, and a protamine hydrolysate can be provided. A medical or dental material for bone formation using this bone-repairing agent can be provided.Type: ApplicationFiled: September 25, 2013Publication date: August 18, 2016Applicant: MARUHA NICHIRO CORPORATIONInventors: Tadao FUKUSHIMA, Jun YAMAZAKI, Jun OHNO, Masako TODA, Makoto MITARAI, Keishi IOHARA
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Publication number: 20160198737Abstract: According to the present invention, a method for recovering useful fish meat proteins from waste water generated during fish paste or fishmeal production is provided. The provided is a method for recovering water-soluble proteins from fish paste leaching waste water or stick water, comprising: adjusting the pH of fish paste leaching waste water or stick water to 4.5-5.5 to insolubilize water-soluble proteins; heating the insolubilized proteins to 30° C. to 90° C. to cause the proteins to flocculate so as to form flocs; subjecting the flocs to solid-liquid separation using a decanter centrifuge during heating; and recovering proteins in the form of solid content.Type: ApplicationFiled: August 8, 2014Publication date: July 14, 2016Applicant: MARUHA NICHIRO CORPORATIONInventors: Kazuya SHIROTA, Ryusuke NAKASHIMA, Shin-ichiro NISHIMOTO, Kenji FUNAKI, Takeshi SUZUKI, Itaru KAWADA
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Publication number: 20160194355Abstract: A peptide compound having a dipeptidyl peptidase-IV (DPPIV) inhibitory activity or a composition containing the peptide compound that can make a contribution to the prevention of the onset of pathology or the progression in diabetes mellitus patients or those at risk of diabetes mellitus can be provided according to the present invention by a simple method using, as a raw material, milt of a fishery product, which has been eaten for ages and has high safety. In the present invention, a peptide compound having a peptidyl peptidase-IV (DPPIV) inhibitory activity obtained in a hydrolysate of a milt protein source obtained from a fishery product is used as an active component of a composition for inhibiting DPPIV.Type: ApplicationFiled: May 19, 2014Publication date: July 7, 2016Applicant: MARUHA NICHIRO CORPORATIONInventors: Yoshinori TAKAHASHI, Akira KAMATA, Tatsuya KONISHI